2-Amino-5-chloro-4-fluorobenzonitrile CAS 1217304-30-7
| CAS No. | 1217304-30-7 |
| Molecular Formula | C7H4ClFN2 |
| Molecular Weight | 170.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Amino-5-chloro-4-fluorobenzonitrile.
CATO supplies 2-Amino-5-chloro-4-fluorobenzonitrile (CAS 1217304-30-7), a certified reference material (molecular formula C7H4ClFN2, MW 170.57 g/mol) for analytical method development and quality control.
Structurally, 2-Amino-5-chloro-4-fluorobenzonitrile (C7H4ClFN2) contains a nitrile group, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 170.57 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Amino-5-chloro-4-fluorobenzonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4ClFN2 |
| Molecular Weight | 170.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 6-Amino-3-chloro-2-fluorobenzonitrile (CAS 1000577-64-9)
- 2-Amino-4-chloro-5-fluorobenzonitrile (CAS 1015427-16-3)
- 4-Amino-2-chloro-6-fluorobenzonitrile (CAS 1095188-13-8)
- 4-Amino-3-chloro-5-fluorobenzonitrile (CAS 1147558-43-7)
- 4-Amino-2-chloro-5-fluorobenzonitrile (CAS 1228376-68-8)
- 5-Amino-2-chloro-4-fluorobenzonitrile (CAS 123614-87-9)
- 2-amino-3-chloro-5-fluorobenzonitrile (CAS 1263277-06-0)
- 4-Amino-5-chloro-2-fluorobenzonitrile (CAS 1443253-03-9)
Recommended Standards
- 4-Chloro-6-fluoro-1H-pyrrolo[2,3-b]pyridine (CAS 1190322-91-8)
- 5-Chloro-6-fluoro pyridine-3-yl-acetonitrile (CAS 1227513-54-3)
- 3-Chloro-6-fluoro-1H-pyrrolo[2,3-b]pyridine (CAS 1190322-84-9)
- 2-(5-Chloro-3-fluoropyridin-2-yl)acetonitrile (CAS 1227572-25-9)
- (3r)-3-Aminopentanoic acid hydrochloride (CAS 952650-02-1)
- (3R,4R,5S,6R)-3-Acetamido-6-(acetoxymethyl)tetrahydro-2H-pyran-2,4,5-triyl triacetate (CAS 14086-90-9)
- 4-Phenyl-4-sulfanyl-2-(trifluoromethyl)butanoic acid (CAS 870703-90-5)
- 2-amino-3-(4-bromo-1H-indol-3-yl)propanoic acid hydrochloride (CAS 1423024-39-8)
- (R)-3,3-Difluoro-2,3-dihydro-1H-inden-1-amine (CAS 1266231-94-0)
- (S)-2-Amino-3-(3-hydroxy-4-methylisoxazol-5-yl)propanoic acid (CAS 211191-53-6)
- 1-Butanoylpiperidine-2-carboxylic acid (CAS 1101848-24-1)
- 4-Chloro-7-(3-(trifluoromethyl)pyridin-2-yl)quinazoline (CAS 573675-83-9)
- 5-chloro-1,2,3,6-tetrahydropyridine hydrochloride (CAS 1909311-91-6)
- Insulin Lispro (CAS 133107-64-9)
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