rac trans-3'-Hydroxy Cotinine-3-carboxylic Acid Methyl Ester CAS 1217641-50-3
| CAS No. | 1217641-50-3 |
| Molecular Formula | C12H14N2O4 |
| Molecular Weight | 250.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including rac trans-3'-Hydroxy Cotinine-3-carboxylic Acid Methyl Ester.
CATO supplies rac trans-3'-Hydroxy Cotinine-3-carboxylic Acid Methyl Ester (CAS 1217641-50-3), a certified reference material (molecular formula C12H14N2O4, MW 250.25 g/mol) for analytical method development and quality control.
The molecular framework of rac trans-3'-Hydroxy Cotinine-3-carboxylic Acid Methyl Ester (C12H14N2O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), rac trans-3'-Hydroxy Cotinine-3-carboxylic Acid Methyl Ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14N2O4 |
| Molecular Weight | 250.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 2 |
Recommended Standards
- Rel-(1R,2S,6S)-6-methyl-4-(3-nitro-4-pyridyl)cyclohex-3-ene-1,2-diol (CAS 1210418-26-0)
- rac cis-3'-Hydroxy Cotinine-3-carboxylic Acid Methyl Ester (CAS 1217778-14-7)
- Rel-(1R,2R,6S)-6-methyl-4-(3-nitro-4-pyridyl)cyclohex-3-ene-1,2-diol (CAS 1210418-25-9)
- Methyl (4-nitrophenyl)-L-prolinate (CAS 122092-19-7)
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- Semaglutide impurity 268 (CAS CATO-C4X-2226268)
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