Ethyl 2-chloro-6-(4-chlorophenyl)nicotinate CAS 1217838-00-0
| CAS No. | 1217838-00-0 |
| Molecular Formula | C14H11Cl2NO2 |
| Molecular Weight | 296.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Ethyl 2-chloro-6-(4-chlorophenyl)nicotinate (CAS 1217838-00-0), molecular formula C14H11Cl2NO2 and molecular weight 296.15 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Ethyl 2-chloro-6-(4-chlorophenyl)nicotinate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 296.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H11Cl2NO2 |
| Molecular Weight | 296.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 6-Chloro-2,3-difluoro-4-(trifluoromethyl)benzaldehyde (CAS 914635-34-0)
- (5E)-5-(3-Isopropoxybenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one 127378-77-2 3441AD C13H13NO2S2 (CAS 127378-77-2)
- tert-Butyl 2-(methylthio)-5,8-dihydropyrido[3,4-d]pyrimidine-7(6H)-carboxylate (CAS 1226776-86-8)
- 2-Bromo-6-chloro-3-(methylthio)benzoic acid (CAS 1823052-34-1)
- N-(4-Amino-2-methylphenyl)-4-methoxybenzamide (CAS 869953-47-9)
- Semaglutide impurity 61 (CAS CATO-C4X-222661)
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