Argatroban Impurity 78 CAS 121785-71-5
| CAS No. | 121785-71-5 |
| Molecular Formula | C23H36N6O5S |
| Molecular Weight | 508.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Argatroban Impurity 78 (CAS 121785-71-5) is a certified pharmaceutical impurity reference standard with the molecular formula C23H36N6O5S and a molecular weight of 508.63 g/mol.
The molecular framework of Argatroban Impurity 78 (C23H36N6O5S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C23H36N6O5S |
| Molecular Weight | 508.63 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Argatroban Standards
- Argatroban (CAS 74863-84-6)
- Argatroban (CAS CATO-C4X-1007104)
- Argatroban Impurity 14 (Mixture of Diastereomers) (CAS 189264-03-7)
- Argatroban Impurity 15 (Mixture of Diastereomers) (CAS CATO-C4X-100715)
- Argatroban Impurity 35 (Mixture of Diastereomers) (CAS CATO-C4X-100735)
- Argatroban Impurity 36 (CAS CATO-C4X-100736)
- Argatroban Impurity 38 (Mixture of Diastereomers) (CAS 189264-02-6)
- Argatroban Impurity 40 (CAS CATO-C4X-100740)
Recommended Standards
- Argatroban Impurity 73 (CAS CATO-C4X-100773)
- Argatroban Impurity 79 (CAS 121785-72-6)
- Argatroban Impurity 6 ( (Mixture of Diastereomers) (CAS 189264-04-8)
- Pentanedioic acid, 1,5-bis[2-[2-(2-butoxyethoxy)ethoxy]ethyl] ester (CAS 65520-42-5)
- Selegiline Impurity 4 (E-Isomer) (CAS CATO-C4X-19164)
- Pitavastatin Impurity 41 (CAS CATO-C4X-103741)
- Octreotide EP Impurity I Acetate (CAS 83795-61-3(Free Base))
- N-(benzo[d][1,3]dioxol-5-yl)-4-(pyridin-2-yl)piperazine-1-carboxamide (CAS 692732-87-9)
- (5-Bromo-3-(trifluoromethyl)pyridin-2-yl)methanamine (CAS 1416768-36-9)
- 2-((2-(Azepan-1-yl)-6-methylpyrimidin-4-yl)oxy)-N-(3-cyanophenyl)acetamide (CAS 1226441-77-5)
- 1-(4-Chloropyridin-2-yl)-2,2,2-trifluoroethan-1-one (CAS 1356086-78-6)
- 10-[4-(1,1-Dimethylethyl)phenyl]-10H-phenothiazine (CAS 883983-86-6)
- 2-((4,8,8-Trimethyl-2-oxo-9,10-dihydro-2h,8h-pyrano[2,3-f]chromen-5-yl)oxy)acetic acid (CAS 888027-28-9)
- Semaglutide impurity 214 (CAS CATO-C4X-2226214)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com