Methyl 2-amino-2-(3-bromo-4-methoxyphenyl)acetate CAS 1218371-85-7
| CAS No. | 1218371-85-7 |
| Molecular Formula | C10H12BrNO3 |
| Molecular Weight | 274.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 2-amino-2-(3-bromo-4-methoxyphenyl)acetate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Methyl 2-amino-2-(3-bromo-4-methoxyphenyl)acetate (CAS 1218371-85-7), molecular formula C10H12BrNO3 and molecular weight 274.11 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, Methyl 2-amino-2-(3-bromo-4-methoxyphenyl)acetate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 274.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 2-amino-2-(3-bromo-4-methoxyphenyl)acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12BrNO3 |
| Molecular Weight | 274.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 2-Amino-1-(8-bromo-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)ethan-1-ol (CAS 1094225-89-4)
- Ethyl 5-amino-2-bromo-4-methoxybenzoate (CAS 1208077-60-4)
- Ethyl 2-amino-3-bromo-6-methoxybenzoate (CAS 1249770-65-7)
- (S)-2-amino-3-(5-bromo-2-methoxyphenyl)propanoic acid (CAS 1270036-47-9)
- (R)-2-amino-3-(5-bromo-2-methoxyphenyl)propanoic acid (CAS 1270185-65-3)
- 2-Amino-3-(4-bromo-1h-pyrazol-1-yl)-2-cyclopropylpropanoic acid (CAS 1340231-17-5)
- Ethyl 2-amino-5-bromo-4-methoxybenzoate (CAS 1538777-93-3)
- 1-Amino-3-(4-bromo-1h-pyrazol-1-yl)cyclopentane-1-carboxylic acid (CAS 1539705-31-1)
Recommended Standards
- Methyl (R)-3-amino-3-(3-bromo-4-hydroxyphenyl)propanoate (CAS 1213099-04-7)
- 2-((5-Bromo-2-methoxyphenyl)(methyl)amino)acetic acid (CAS 1218645-43-2)
- Methyl 4-bromo-1-(((dimethylamino)methylene)amino)-1H-pyrrole-2-carboxylate (CAS 1221420-14-9)
- 2-Bromo-4-isopropoxy-5-nitrotoluene (CAS 1202858-68-1)
- 3-(2-Pyridyl)acrylic Acid, Predominantly trans (CAS 54495-51-1)
- Acetic acid-<SUP>18</SUP>O<SUB>2</SUB> (CAS 17217-83-3)
- (2E)-3-Methyl-3-(methylamino)butan-2-one oxime (CAS 90713-76-1)
- 3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrazol-5-amine hydrochloride (CAS 1031793-23-3)
- Adapalene Impurity 11 (CAS CATO-C4X-180911)
- N-cyclohexylpiperazine-1-sulfonamide (CAS 1042643-23-1)
- 4-Ethyl-2-(2-morpholinoethyl)-6-phenylpyridazin-3(2H)-one hydrochloride (CAS 33147-47-6)
- (4-Bromo-1H-pyrrolo[2,3-c]pyridin-7-yl)methanimine (CAS 1352395-21-1)
- 1-(6-bromo-3-fluoropyridin-2-yl)ethan-1-ol (CAS 1403468-45-0)
- Neuropeptide VF (124-131) (human) (CAS 311309-27-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com