2-(5-Bromo-2-fluorophenyl)-2-(dimethylamino)acetic acid CAS 1218655-13-0
| CAS No. | 1218655-13-0 |
| Molecular Formula | C10H11BrFNO2 |
| Molecular Weight | 276.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(5-Bromo-2-fluorophenyl)-2-(dimethylamino)acetic acid.
2-(5-Bromo-2-fluorophenyl)-2-(dimethylamino)acetic acid (CAS 1218655-13-0), molecular formula C10H11BrFNO2 and molecular weight 276.10 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(5-Bromo-2-fluorophenyl)-2-(dimethylamino)acetic acid (C10H11BrFNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11BrFNO2 |
| Molecular Weight | 276.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- (2-Isopropoxy-4-methylphenyl)methanol (CAS 2056110-35-9)
- Ethyl 2-(((((9H-fluoren-9-yl)methoxy)carbonyl)oxy)imino)-2-cyanoacetate (CAS 1235983-26-2)
- 3-[(4,6-Dimethoxypyrimidin-2-yl)oxy]pyridine-2-carboxylic acid monohydrate (CAS 113582-66-4)
- 4-(2-Bromo-5-chlorophenyl)but-3-en-2-one (CAS 1563091-09-7)
- 1-Bromo-8-(methoxymethyl)naphthalene (CAS 135190-16-8)
- 2-(2,6-Dichloro-9H-purin-8-yl)propan-2-ol (CAS 1382981-71-6)
- Myelin Basic Protein (85-99) Peptide Antagonist (CAS 444305-16-2)
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