(3R,4S)-1-(tert-Butoxycarbonyl)-4-(4-fluorophenyl)pyrrolidine-3-carboxylic acid CAS 1218764-13-6
| CAS No. | 1218764-13-6 |
| Molecular Formula | C16H20FNO4 |
| Molecular Weight | 309.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (3R,4S)-1-(tert-Butoxycarbonyl)-4-(4-fluorophenyl)pyrrolidine-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(3R,4S)-1-(tert-Butoxycarbonyl)-4-(4-fluorophenyl)pyrrolidine-3-carboxylic acid (CAS 1218764-13-6), molecular formula C16H20FNO4 and molecular weight 309.33 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, (3R,4S)-1-(tert-Butoxycarbonyl)-4-(4-fluorophenyl)pyrrolidine-3-carboxylic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 309.33 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H20FNO4 |
| Molecular Weight | 309.33 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- trans-1-(tert-Butoxycarbonyl)-4-(4-fluorophenyl)pyrrolidine-3-carboxylic acid (CAS 1218764-11-4)
- 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 1224844-38-5)
- Ethyl 4-(4-fluorophenyl)-2-methylquinoline-3-carboxylate (CAS 121659-70-9)
- (3aR,4S,9bS)-4-(4-fluorophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-cArboxylic acid (CAS 1391570-73-2)
- DL-3-Camphorcarboxylic acid (CAS 474-98-6)
- (2E)-2-Cyano-3-[2-(2,4-dichlorophenoxy)phenyl]prop-2-enethioamide (CAS 866019-93-4)
- 2-(3-Chloro-4-fluorobenzenesulfonamido)-4-(methylsulfanyl)butanoic acid (CAS 1009235-46-4)
- N-Benzyl-2-iodoaniline (CAS 76464-99-8)
- 3-Iodo-1-propylpyrazole (CAS 1334500-09-2)
- Lofentanil-d3 Oxalate (1.0mg/ml in Acetonitrile) (CAS 1346599-64-1)
- (2-Chloro-6-methoxypyridin-3-yl)boronic acid (CAS 1072946-25-8)
- Ethyl 7-(2,4-dichlorophenyl)-7-oxoheptanoate (CAS 898778-02-4)
- Ethyl 3-(3-hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate (CAS 2760262-15-3)
- Semaglutide impurity 78 (CAS CATO-C4X-222678)
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