4-(4-Fluoro-2-(trifluoromethyl)phenyl)picolinonitrile CAS 1219454-47-3
| CAS No. | 1219454-47-3 |
| Molecular Formula | C13H6F4N2 |
| Molecular Weight | 266.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4-(4-Fluoro-2-(trifluoromethyl)phenyl)picolinonitrile (CAS 1219454-47-3), molecular formula C13H6F4N2 and molecular weight 266.19 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 4-(4-Fluoro-2-(trifluoromethyl)phenyl)picolinonitrile is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 266.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C13H6F4N2 |
| Molecular Weight | 266.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 4-(2-Fluoro-5-(trifluoromethyl)phenyl)picolinonitrile (CAS 1219454-31-5)
- 4-(4-Fluoro-3-(trifluoromethyl)phenyl)picolinonitrile (CAS 1219454-49-5)
- 4-(3-Fluoro-2-(trifluoromethyl)phenyl)picolinonitrile (CAS 1219454-57-5)
- 2-Fluoro-3-isopropoxy-5-(trifluoromethyl)benzoic acid (CAS 2432848-76-3)
- 3-Fluoro-4-isopropoxy-5-(trifluoromethyl)benzoic acid (CAS 2624417-09-8)
- 3-Fluoro-5-(pentafluorosulfur)benzoic acid (CAS 1240256-86-3)
- 2-Fluoro-4-(pentafluoro-lambda6-sulfanyl)benzoic acid (CAS 1240257-03-7)
- 2-Fluoro-5-(pentafluorothio)benzoic acid (CAS 1240257-15-1)
Recommended Standards
- 3-(2-Fluorophenyl)-5-(trifluoromethyl)picolinonitrile (CAS 1214380-38-7)
- 5-(4-Fluorophenyl)-3-(trifluoromethyl)picolinonitrile (CAS 1214380-36-5)
- (4,4-difluorocyclohexen-1-yl) trifluoromethanesulfonate (CAS 1227068-83-8)
- 5-(3-Fluorophenyl)-3-(trifluoromethyl)picolinonitrile (CAS 1214368-08-7)
- 8-Oh-dpat (CAS 78950-78-4)
- 4-Chloro-2-(dimethylamino)pyridine (CAS 735255-56-8)
- 2-((5-(2-Bromophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-chlorophenyl)acetamide (CAS 332388-16-6)
- (S)-1-(2-fluorophenyl)butan-1-amine (CAS 1212922-49-0)
- Onitisin (CAS 53823-03-3)
- trans-2-Methyl-3-Phenyl-Aziridine (CAS 20993-60-6)
- tert-Butyl 15-bromopentadecanoate (CAS 905302-64-9)
- Methyl 2,2-dimethyl-5-oxopyrrolidine-1-carboxylate (CAS 247233-29-0)
- (1-Methyl-1H-benzo[d][1,2,3]triazol-7-yl)methanamine (CAS 1557550-85-2)
- Mitogenic Pentapeptide (CAS 87173-03-3)
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