4-(5-Methoxy-2-(trifluoromethyl)phenyl)picolinonitrile CAS 1219454-65-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1219454-65-5
Molecular FormulaC14H9F3N2O
Molecular Weight278.23 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(5-Methoxy-2-(trifluoromethyl)phenyl)picolinonitrile CAS 1219454-65-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(5-Methoxy-2-(trifluoromethyl)phenyl)picolinonitrile.

CATO supplies 4-(5-Methoxy-2-(trifluoromethyl)phenyl)picolinonitrile (CAS 1219454-65-5), a certified reference material (molecular formula C14H9F3N2O, MW 278.23 g/mol) for analytical method development and quality control.

4-(5-Methoxy-2-(trifluoromethyl)phenyl)picolinonitrile (C14H9F3N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-(5-Methoxy-2-(trifluoromethyl)phenyl)picolinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H9F3N2O
Molecular Weight278.23 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms2

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