(11bS)-2,6-bis[4-(1,1-dimethylethyl)-2,6-bis(1-methylethyl)phenyl]-4-hydroxy-4-oxide-4λ5-Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin CAS 1219498-54-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1219498-54-0
Molecular FormulaC52H61O4P
Molecular Weight781.01 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(11bS)-2,6-bis[4-(1,1-dimethylethyl)-2,6-bis(1-methylethyl)phenyl]-4-hydroxy-4-oxide-4λ5-Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin CAS 1219498-54-0 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

(11bS)-2,6-bis[4-(1,1-dimethylethyl)-2,6-bis(1-methylethyl)phenyl]-4-hydroxy-4-oxide-4λ5-Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin (CAS 1219498-54-0) is a high-purity analytical reference standard with the molecular formula C52H61O4P and a molecular weight of 781.01 g/mol.

The molecular framework of (11bS)-2,6-bis[4-(1,1-dimethylethyl)-2,6-bis(1-methylethyl)phenyl]-4-hydroxy-4-oxide-4λ5-Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin (C52H61O4P) is characterized by a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC52H61O4P
Molecular Weight781.01 g/mol
Purity97%+
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)22.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990

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