2-[2-(2-Piperidinyl)ethyl]-1,2,3,4-tetrahydroisoquinoline dihydrochloride CAS 1219981-00-6
| CAS No. | 1219981-00-6 |
| Molecular Formula | C16H24N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-[2-(2-Piperidinyl)ethyl]-1,2,3,4-tetrahydroisoquinoline dihydrochloride (CAS 1219981-00-6), molecular formula C16H24N2HCl and molecular weight 280.84 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 2-[2-(2-Piperidinyl)ethyl]-1,2,3,4-tetrahydroisoquinoline dihydrochloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 280.84 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-[2-(2-Piperidinyl)ethyl]-1,2,3,4-tetrahydroisoquinoline dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H24N2 2*HCl |
| Molecular Weight | 280.84 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Piperidinyl Standards
- 2-[(1-Methyl-4-piperidinyl)oxy]-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine (CAS 1015242-42-8)
- 2-(2-Methyl-1-piperidinyl)isonicotinic acid (CAS 1019127-10-6)
- 2-(4-Methyl-1-piperidinyl)isonicotinic acid (CAS 1019387-13-3)
- 4-(2-Methyl-1-piperidinyl)-3-nitrobenzoic acid (CAS 1019461-42-7)
- 2-(2-Methyl-1-piperidinyl)nicotinic acid (CAS 1019461-43-8)
- 6-(4-Piperidinyl)quinoline (CAS 1020277-40-0)
- 4-[2-(1-Piperidinyl)ethoxy]benzophenone (CAS 102156-42-3)
- 103660-47-5 Methyl 4-[3-(4-piperidinyl)-1H-pyrazol-5-yl]phenyl ether MFCD00665098 (CAS 103660-47-5)
Recommended Standards
- 1 4-BIS(TRIETHOXYSILYL)BENZENE 1,4-bis(triethoxysilyl)benzene 2615-18-1 (CAS 2615-18-1)
- 1-Ethynyl-2-fluoro-4-methylbenzene (CAS 928304-42-1)
- N1,N1-dimethylbicyclo[1.1.1]Pentane-1,3-diamine hydrochloride (CAS 2231674-46-5)
- (3-Bromophenyl)(2,3-dimethylphenyl)methanol (CAS 1285480-74-1)
- 7-(3-Hydroxy-5-oxocyclopent-1-en-1-yl)heptanoic acid (CAS 22099-78-1)
- 3-(4-Trifluoromethyl-pyridin-2-yl)-benzoic acidmethyl ester (CAS 1299607-42-3)
- (1S,2R)-Methyl 1-amino-2-isopropylcyclopropanecarboxylate (CAS 765244-35-7)
- Mianserin EP Impurity D (CAS 157994-98-4)
- 4-Bromopyrene (CAS 1732-26-9)
- Hexapeptide-1 (CAS CATO-CPTD788821)
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