(E)-(3-(4-Hydroxy-3-methoxyphenyl)acryloyl)glycine CAS 1220-05-9
| CAS No. | 1220-05-9 |
| Molecular Formula | C12H13NO5 |
| Molecular Weight | 251.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-(3-(4-Hydroxy-3-methoxyphenyl)acryloyl)glycine.
(E)-(3-(4-Hydroxy-3-methoxyphenyl)acryloyl)glycine (CAS 1220-05-9) is a high-purity analytical reference standard with the molecular formula C12H13NO5 and a molecular weight of 251.24 g/mol.
Based on its molecular formula C12H13NO5, (E)-(3-(4-Hydroxy-3-methoxyphenyl)acryloyl)glycine contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 251.24 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (E)-(3-(4-Hydroxy-3-methoxyphenyl)acryloyl)glycine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H13NO5 |
| Molecular Weight | 251.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related E Standards
- 4-Hydroxy-1-(2-hydroxybenzoyl)pyrrolidine-2-carboxylic acid (CAS 1102902-78-2)
- 6-Hydroxy-2-(methoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (CAS 1219199-11-7)
- 3-(3-Hydroxy-4-(hydroxymethyl)cyclopentyl)-2H-[1,2,3]triazolo[4,5-d]pyrimidin-7(3H)-one (CAS 50767-24-3)
- 3-Hydroxy-5-((5-hydroxy-1,4,5,6-tetrahydropyrimidin-2-yl)amino)benzoic acid (CAS 240431-49-6)
- 5-Hydroxy-2-(tetrahydrofuran-2-carboxamido)benzoic acid (CAS 667409-89-4)
- Methyl 4-(5-hydroxy-5-methyl-3-oxoisoxazolidin-2-yl)benzoate (CAS 371166-28-8)
- N-hydroxy-2-((3-(trifluoromethyl)pyridin-2-yl)thio)acetimidamide (CAS 263762-04-5)
- 5-(3-Hydroxy-4-methoxybenzylidene)thiazolidine-2,4-dione (CAS 184840-76-4)
Recommended Standards
- Methyl (2S)-1-(5-nitro-2-pyridinyl)tetrahydro-1H-pyrrole-2-carboxylate (CAS 122092-22-2)
- 1-(6-Oxo-1,6-dihydropyridazine-3-carbonyl)piperidine-2-carboxylic acid (CAS 1218456-77-9)
- 9-((2R,4S,5S)-4-Amino-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one (CAS 1222689-74-8)
- 3-Nitro-4-(piperazin-1-yl)benzoic acid (CAS 1216416-11-3)
- Bazedoxifene Impurity E (CAS 857594-21-9)
- Ethyl 3-amino-7-bromofuro[3,2-c]pyridine-2-carboxylate (CAS 2091217-61-5)
- 4-Chloro-2-methylpyridine 1-oxide (CAS 696-08-2)
- Methyl N-{1-oxo-2-[(pyridin-3-yl)methyl]-1,2-dihydroisoquinolin-4-yl}carbamate (CAS 303995-38-2)
- 4-(Methylsulfonyl)-1h-pyrrole-2-sulfonyl chloride (CAS 1208447-29-3)
- Methyl 2-amino-3-chloro-5-(trifluoromethoxy)benzoate (CAS 1003708-08-4)
- methyl 3-(1H-indol-3-yl)-2-(naphthalen-2-ylformamido)propanoate (CAS 1396968-43-6)
- 2-(4-Methoxyphenyl)-1H-1,3-benzodiazol-1-ol (CAS 10066-15-6)
- Tert-butyl (E)-5-(3-methoxy-3-oxoprop-1-en-1-yl)-1H-indole-1-carboxylate (CAS 561307-71-9)
- (Des-Thr7)-Glucagon trifluoroacetate salt (CAS 1802078-28-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com