4-{[(2,6-Difluorobenzyl)oxy]methyl}piperidinehydrochloride CAS 1220020-16-5
| CAS No. | 1220020-16-5 |
| Molecular Formula | C13H17F2NO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-{[(2,6-Difluorobenzyl)oxy]methyl}piperidinehydrochloride.
4-{[(2,6-Difluorobenzyl)oxy]methyl}piperidinehydrochloride (CAS 1220020-16-5) is a high-purity analytical reference standard with the molecular formula C13H17F2NOHCl and a molecular weight of 277.74 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 4-{[(2,6-Difluorobenzyl)oxy]methyl}piperidinehydrochloride is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 277.74 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-{[(2,6-Difluorobenzyl)oxy]methyl}piperidinehydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H17F2NO HCl |
| Molecular Weight | 277.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Difluorobenzyl Standards
- (R)-1-(3,4-Difluorobenzyl)-2-oxo-N-(2-((2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)oxy)-1-phenylethyl)-1,2-dihydropyridine-3-carboxamide (CAS 1001409-50-2)
- Ethyl 1-(3,4-difluorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxylate (CAS 1001412-63-0)
- 1-(3,4-Difluorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxylic Acid (CAS 1001413-01-9)
- 1-(3,4-Difluorobenzyl)-2-oxo-N-(thiophen-2-ylmethyl)-1,2-dihydropyridine-3-carboxamide (CAS 1001413-87-1)
- Methyl 1-(3,4-difluorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxylate (CAS 1001414-50-1)
- n-(3,5-Difluorobenzyl)-1-(1-methyl-1h-pyrazol-4-yl)methanamine (CAS 1006436-32-3)
- N-(3,5-difluorobenzyl)-1-(1,3-dimethyl-1H-pyrazol-4-yl)methanamine (CAS 1006436-76-5)
- n-(2,5-Difluorobenzyl)-1-(1,3-dimethyl-1h-pyrazol-4-yl)methanamine (CAS 1006449-75-7)
Recommended Standards
- 5-(4-Amidinophenoxy)pentanoic Acid (CAS 144602-61-9)
- 2-Fluoro-5-(methoxycarbonyl)phenylboronic Acid (CAS 850568-04-6)
- 8-Methoxy-2,4-dimethylquinoline (CAS 84264-26-6)
- 3-Bromo-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 83255-86-1)
- 2-Ethylbutanamide (CAS 1114-38-1)
- 2-[(pyrimidin-4-yl)amino]ethan-1-ol (CAS 1640-87-5)
- 7-Bromo-3-methyl-1,2-benzisoxazole (CAS 66033-75-8)
- 4-Phenyl-3-((4-phenylpiperazin-1-yl)methyl)dihydrofuran-2(3H)-one (CAS 99518-89-5)
- (R)-2-(Naphthalen-2-yl)propanoic acid (CAS 67021-79-8)
- Des-[Gly]31-Semaglutide (CAS CATO-C4X-2226156)
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