N-[4-(4-Piperidinylmethoxy)phenyl]acetamidehydrochloride CAS 1220033-86-2
| CAS No. | 1220033-86-2 |
| Molecular Formula | C14H20N2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-[4-(4-Piperidinylmethoxy)phenyl]acetamidehydrochloride (C14H20N2O2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
N-[4-(4-Piperidinylmethoxy)phenyl]acetamidehydrochloride (CAS 1220033-86-2), molecular formula C14H20N2O2HCl and molecular weight 284.78 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H20N2O2 HCl |
| Molecular Weight | 284.78 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- Methyl 3-(4-piperidinylmethoxy)benzoatehydrochloride (CAS 1184976-73-5)
- 3-(4-Piperidinylmethoxy)pyridinedihydrochloride (CAS 1185087-06-2)
- N-[3-(4-Piperidinylmethoxy)phenyl]acetamidehydrochloride (CAS 1185173-56-1)
- 8-(4-Piperidinylmethoxy)quinoline dihydrochloride (CAS 1185298-73-0)
- 8-(3-Piperidinylmethoxy)quinoline dihydrochloride (CAS 1211513-32-4)
- 3-[(3-Piperidinylmethoxy)methyl]piperidine dihydrochloride (CAS 1211514-21-4)
- 4-[(4-Piperidinylmethoxy)methyl]piperidine dihydrochloride (CAS 1211514-33-8)
- Ethyl 3-(4-piperidinylmethoxy)benzoatehydrochloride (CAS 1219960-86-7)
Recommended Standards
- Allyl 3-(methylamino)benzoate (CAS 153775-51-0)
- N-(4-methoxybenzo[d]thiazol-2-yl)acetamide (CAS 90915-52-9)
- 5-Bromogramine (CAS 830-93-3)
- Atorvastatin EP Impurity C Sodium Salt (CAS 1807481-00-0)
- 6-Bromo-3-methylimidazo[1,5-a]pyridine (CAS 1526517-09-8)
- Methanaminium, N,N'-[2-[(dimethylamino)methylene]-1,3-propanediylidene]bis[N-methyl-, dichloride (CAS 404869-59-6)
- 3-(N,N-Dipropyl)amino-N-methylsulfonylaniline (CAS 186453-43-0)
- N-Cyclohexylpyridin-4-amine (CAS 34844-87-6)
- Clopidogrel Impurity 85 (CAS 1219432-42-4)
- Semaglutide (CAS CATO-C4X-2226105)
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