3-{[4-(Trifluoromethyl)phenoxy]methyl}piperidinehydrochloride CAS 1220037-57-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1220037-57-9
Molecular FormulaC13H16F3NO
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-{[4-(Trifluoromethyl)phenoxy]methyl}piperidinehydrochloride CAS 1220037-57-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 295.73 g/mol gives 3-{[4-(Trifluoromethyl)phenoxy]methyl}piperidinehydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

3-{[4-(Trifluoromethyl)phenoxy]methyl}piperidinehydrochloride (CAS 1220037-57-9) is a high-purity analytical reference standard with the molecular formula C13H16F3NOHCl and a molecular weight of 295.73 g/mol.

3-{[4-(Trifluoromethyl)phenoxy]methyl}piperidinehydrochloride (C13H16F3NOHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-{[4-(Trifluoromethyl)phenoxy]methyl}piperidinehydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H16F3NO HCl
Molecular Weight295.73 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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