6-((2,4-Difluorophenyl)amino)-2-formylnicotinonitrile CAS 1221271-90-4
| CAS No. | 1221271-90-4 |
| Molecular Formula | C13H7F2N3O |
| Molecular Weight | 259.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-((2,4-Difluorophenyl)amino)-2-formylnicotinonitrile (C13H7F2N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
6-((2,4-Difluorophenyl)amino)-2-formylnicotinonitrile (CAS 1221271-90-4) is a high-purity analytical reference standard with the molecular formula C13H7F2N3O and a molecular weight of 259.21 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-((2,4-Difluorophenyl)amino)-2-formylnicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H7F2N3O |
| Molecular Weight | 259.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Difluorophenyl Standards
- 2-[5-(2,6-Difluorophenyl)-1,2,4-oxadiazol-3-yl]pyridine (CAS 339103-07-0)
- 4-[5-(2,6-Difluorophenyl)-1,2,4-oxadiazol-3-yl]pyridine (CAS 339104-55-1)
- 2-(2,4-Difluorophenyl)-5-(trifluoromethyl)pyridine (CAS 387827-64-7)
- 2-(2,6-Difluorophenyl)-2,3-dihydroquinolin-4(1H)-one (CAS 1956376-67-2)
- [1-(2,4-difluorophenyl)-3-(ethylsulfanyl)propan-2-yl](ethyl)amine (CAS 1490532-16-5)
- 3-(2,4-Difluorophenyl)-5,6,7,8-tetrahydro-5,8-methanocinnoline (CAS 918873-58-2)
- 4-(3,5-Difluorophenyl)-3-(methylsulfonyl)-1H-pyrazole (CAS 1708037-20-0)
- Bis(3,5-difluorophenyl)sulfane (CAS 1801970-32-0)
Recommended Standards
- Platinum(IV) sulfide (CAS 12038-21-0)
- 5-(4-Carboxyphenyl)-2-hydroxyisonicotinic acid (CAS 1261998-76-8)
- 1172235-73-2 2-(2-Formyl-1H-pyrrol-1-yl)terephthalic acid MFCD14281669 (CAS 1172235-73-2)
- 2-(S-Butylthiomethyl)-1-bromobenzene (CAS 1309978-21-9)
- 5-(1,1-Difluoroethyl)-1-methyl-1H-pyrazole-3-carboxylic acid (CAS 1024599-62-9)
- 2-Phenyl-6-(trifluoromethyl)quinoline-4-carbonitrile (CAS 1416439-23-0)
- (4-(Cyclopropylsulfonyl)phenyl)boronic acid (CAS 1217501-07-9)
- 2-(Difluoromethyl)-6-hydroxy-4-methylpyridine-3-carbonyl chloride (CAS 1805534-72-8)
- 4-Chloro-6-((4-methoxyphenyl)thio)-2-(methylthio)pyrimidine (CAS 478258-40-1)
- 5-Isopropyl-1,2,4-oxadiazol-3(2H)-one (CAS 55375-87-6)
- 5-(Chloromethyl)-3-phenyl-1H-pyrazole hydrochloride (CAS 493038-58-7)
- (R)-1-(2,6-dichlorophenyl)ethan-1-amine (CAS 1131737-05-7)
- Cy7.5 diacid(diso3) (CAS 752189-27-8)
- 59880-97-6 Chemotactic peptide F-Met-Leu-Phe L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)- N-Formyl-L-methionyl-L-leucyl-L-phenylalanine N-Formyl-Met-Leu-Phe N-Formylmethionine leucyl-phenylalanine fMLF fMLP (misnomer but widely used) (CAS 59880-97-6)
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