4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)sulfinyl)aniline CAS 1221792-80-8
| CAS No. | 1221792-80-8 |
| Molecular Formula | C12H8ClF3N2OS |
| Molecular Weight | 320.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)sulfinyl)aniline is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)sulfinyl)aniline (CAS 1221792-80-8), a certified reference material (molecular formula C12H8ClF3N2OS, MW 320.72 g/mol) for analytical method development and quality control.
The molecular framework of 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)sulfinyl)aniline (C12H8ClF3N2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)sulfinyl)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8ClF3N2OS |
| Molecular Weight | 320.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 6-(2-Chloro-5-fluoropyrimidin-4-yl)-1-cyclopropyl-4-fluoro-2-methyl-1H-benzo[d]imidazole (CAS 1231930-43-0)
- 2'-Chloro-4-methoxy-5'-(methoxycarbonyl)-[1,1'-biphenyl]-2-carboxylic acid (CAS 1261917-20-7)
- 6-Chloro-7-cyclobutyl-3-(2,6-difluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1351952-76-5)
- (1-(3-Chloro-4-fluorophenyl)-3-(4-fluorophenyl)-1H-pyrazol-4-yl)methanol (CAS 618444-43-2)
- (E)-3-(5-chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)-1-(thiophen-2-yl)prop-2-en-1-one (CAS 956376-49-1)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(thiophen-2-yl)acetamide (CAS 861211-80-5)
- 2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(2-thienyl)acetaldehyde oxime (CAS 338770-64-2)
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Recommended Standards
- rac Efavirenz-d5(major) (CAS 1132642-95-5)
- 4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-sulfonylchloride (CAS 524046-23-9)
- 4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-sulfonyl chloride (CAS 731779-91-2)
- 3'-(Trifluoromethyl)biphenyl-4-sulfonyl chloride (CAS 885267-96-9)
- 5-Chloro-2-hydroxybenzenesulfonamide (CAS 82020-64-2)
- 2-Bromomethyl-1,3-dioxolane (CAS 4360-63-8)
- 1-Benzyl-4-hydroxy-6-carbomoyl-5-azaindole (CAS 1000342-24-4)
- 2-Hydroxy-2,6-bis(trifluoromethyl)-2,3-dihydro-4H-pyran-4-one (CAS 933795-21-2)
- (Pyridin-3-yl)thiourea (CAS 30162-37-9)
- 5-(Benzyloxy)-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid (CAS 1338091-25-0)
- Nitrazepam (CAS 146-22-5)
- 2’-Methoxy-4’-nitrophenylAcetophenone (CAS 90564-14-0)
- N-(2-(Piperidin-1-yl)ethyl)-7-(trifluoromethyl)quinolin-4-amine (CAS 289628-56-4)
- [α-Glu](Sidechain trans-position)-Liraglutide (CAS CATO-C4X-199240)
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