2-(o-Tolyloxy)-4H-benzo[d][1,3,2]dioxaphosphinine 2-oxide CAS 1222-87-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1222-87-3
Molecular FormulaC14H13O4P
Molecular Weight276.22 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(o-Tolyloxy)-4H-benzo[d][1,3,2]dioxaphosphinine 2-oxide CAS 1222-87-3 chemical structure

Description

2-(o-Tolyloxy)-4H-benzo[d][1,3,2]dioxaphosphinine 2-oxide (C14H13O4P) contains a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

2-(o-Tolyloxy)-4H-benzo[d][1,3,2]dioxaphosphinine 2-oxide (CAS 1222-87-3), molecular formula C14H13O4P and molecular weight 276.22 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-(o-Tolyloxy)-4H-benzo[d][1,3,2]dioxaphosphinine 2-oxide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC14H13O4P
Molecular Weight276.22 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957

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