2-(Chloromethyl)-6-(trifluoromethyl)pyridine hydrochloride CAS 1222556-74-2

Description

Compared with other compounds in its class, the molecular weight of 232.03 g/mol gives 2-(Chloromethyl)-6-(trifluoromethyl)pyridine hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-(Chloromethyl)-6-(trifluoromethyl)pyridine hydrochloride (CAS 1222556-74-2) is a high-purity analytical reference standard with the molecular formula C7H5ClF3NHCl and a molecular weight of 232.03 g/mol.

The molecular framework of 2-(Chloromethyl)-6-(trifluoromethyl)pyridine hydrochloride (C7H5ClF3NHCl) is characterized by a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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