Pantoprazole Impurity 22 CAS 122307-41-9
| CAS No. | 122307-41-9 |
| Molecular Formula | C7H8ClNO2 |
| Molecular Weight | 173.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Pantoprazole Impurity 22.
Pantoprazole Impurity 22 (CAS 122307-41-9) is a certified pharmaceutical impurity reference standard with the molecular formula C7H8ClNO2 and a molecular weight of 173.60 g/mol.
Pantoprazole Impurity 22 (C7H8ClNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H8ClNO2 |
| Molecular Weight | 173.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Pantoprazole Standards
- Pantoprazole Impurity 73 (CAS CATO-C4X-139973)
- Pantoprazole Impurity 29 (CAS 172282-50-7)
- Pantoprazole Impurity 52 (CAS 72830-08-1)
- Pantoprazole Impurity 53 (CAS 72830-07-0)
- Pantoprazole Impurity 24 (CAS 15931-25-6)
- Pantoprazole related impurity G (CAS 169905-10-6)
- Pantoprazole Impurity 59 (CAS 562074-62-8)
- Pantoprazole Impurity 42 (CAS 107512-34-5)
Recommended Standards
- 872358-20-8 5-(Chloromethyl)-N-methylfuran-2-carboxamide DTXSID20672460 (CAS 872358-20-8)
- n-[(5-chloro-1,3-dimethyl-1h-pyrazol-4-yl)methylidene]hydroxylamine (CAS 590410-59-6)
- Atrazine-Desisopropyl (CAS 1007-28-9)
- N-[(5-chloro-1,3-dimethyl-1H-pyrazol-4-yl)methylidene]hydroxylamine (CAS 27006-86-6)
- Hyoscyamine Impurity 4 (CAS CATO-C4X-34374)
- Daprodustat Impurity 18 (CAS 117043-46-6)
- Revefenacin Impurity 12 Formate (CAS CATO-C4X-203142)
- 2-Chloro-1-(3,3-difluoropyrrolidin-1-yl)ethan-1-one (CAS 1391809-92-9)
- 5-(Hex-5-en-1-yl)-3-methylisoxazole (CAS 134836-81-0)
- (R)-6-chloro-4-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridazin-3-amine (CAS 1370651-29-8)
- 3-(4-Methoxyphenyl)-3-phenylpropanoic acid (CAS 114327-14-9)
- Carfilzomib Impurity N2 (CAS 1396006-45-3)
- ((1R,2S)-2-(Trifluoromethyl)cyclopropyl)methanol (CAS 1416432-55-7)
- [5-31]-Semaglutide (CAS CATO-C4X-2226263)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com