3-(2,5-Dichloropyrimidin-4-yl)pyrazolo[1,5-a]pyridine CAS 1224709-13-0
| CAS No. | 1224709-13-0 |
| Molecular Formula | C11H6Cl2N4 |
| Molecular Weight | 265.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 3-(2,5-Dichloropyrimidin-4-yl)pyrazolo[1,5-a]pyridine (CAS 1224709-13-0), a certified reference material (molecular formula C11H6Cl2N4, MW 265.10 g/mol) for analytical method development and quality control.
3-(2,5-Dichloropyrimidin-4-yl)pyrazolo[1,5-a]pyridine (C11H6Cl2N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H6Cl2N4 |
| Molecular Weight | 265.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Dichloropyrimidin Standards
- 3-(4,5-Dichloropyrimidin-2-yl)pyrazolo[1,5-a]pyridine (CAS 1331768-91-2)
- 1-(2,5-Dichloropyrimidin-4-yl)-1H-benzo[d]imidazole (CAS 882562-56-3)
- 3-(2,5-Dichloropyrimidin-4-yl)imidazo[1,2-a]pyridine (CAS 882562-65-4)
- 4-((4,6-Dichloropyrimidin-2-yl)amino)benzonitrile (CAS 329187-59-9)
- 1-(2,5-Dichloropyrimidin-4-yl)-1H-indole (CAS 293292-36-1)
- 3-(2,5-Dichloropyrimidin-4-yl)-1H-indole (CAS 937366-57-9)
- 2-((4,6-Dichloropyrimidin-2-yl)thio)ethyl acetate (CAS 50892-12-1)
- (4,6-Dichloropyrimidin-5-yl)(2-methylpyridin-3-yl)methanone (CAS 1416373-37-9)
Recommended Standards
- 7-BROMO-3-METHOXY-2-NAPHTHALDEHYDE (CAS 1219689-98-1)
- 5,7-Dichloro-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine (CAS 1232224-67-7)
- (S)-2,2,2-Trifluoro-1-(perfluorophenyl)ethan-1-amine (CAS 1213192-93-8)
- 4-[(4,6-Dichloro-2-pyrimidinyl)amino]benzonitrile-13C3 (CAS 1246818-77-8)
- 2-Fluoro-6-methoxy-4-phenylpyridine (CAS 1803823-53-1)
- N1,N1,2-Trimethylbenzene-1,4-diamine (CAS 27746-11-8)
- 3-Chloro-N-phenyl-5-(trifluoromethyl)-2-pyridinamine (CAS 1163681-50-2)
- 2-(2,2,2-Trifluoroethoxy)-5-(trifluoromethyl)cyclohexan-1-amine (CAS 1005044-04-1)
- 2-(2-Ethoxynaphthalen-1-yl)ethan-1-ol (CAS 1443355-56-3)
- 4-[3-(Trifluoromethyl)phenyl]-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)pyridine-3-carbonitrile (CAS 478245-79-3)
- N-(3-Aminopropyl)-N-(2-cyclopentylethyl)isoquinoline-5-sulfonamide (CAS 651307-32-3)
- 7-Methoxy-8-methylquinolin-4-ol (CAS 872497-14-8)
- 1,5-Diamino-2,6-dibromoanthracene-9,10-dione (CAS 106782-84-7)
- Myristoyl Pentapeptide -4 acetate (CAS 959610-30-1(free base))
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