3-Bromo-8,8-dimethyl-8H-indolo[3,2,1-de]acridine CAS 1224892-52-7

Description

The occurrence of 3-Bromo-8,8-dimethyl-8H-indolo[3,2,1-de]acridine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

3-Bromo-8,8-dimethyl-8H-indolo[3,2,1-de]acridine (CAS 1224892-52-7), molecular formula C21H16BrN and molecular weight 362.26 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 3-Bromo-8,8-dimethyl-8H-indolo[3,2,1-de]acridine (C21H16BrN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-Bromo-8,8-dimethyl-8H-indolo[3,2,1-de]acridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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