Bisoprolol EP Impurity C CAS 1225195-70-9
| CAS No. | 1225195-70-9 |
| Molecular Formula | C25H38N2O4 |
| Molecular Weight | 430.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Bisoprolol EP Impurity C (CAS 1225195-70-9), a pharmacopoeial impurity reference standard (molecular formula C25H38N2O4, MW 430.58 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Bisoprolol EP Impurity C (C25H38N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H38N2O4 |
| Molecular Weight | 430.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 2 |
Related Bisoprolol Standards
- Bisoprolol Impurity 55 (CAS 2417155-08-7)
- Bisoprolol Impurity 112 (CAS CATO-C4X-1247112)
- Bisoprolol Impurity 113 (CAS CATO-C4X-1247113)
- Bisoprolol Impurity 123 (CAS CATO-C4X-1247123)
- Bisoprolol Impurity 58 (CAS CATO-C4X-124758)
- Bisoprolol EP Impurity D (CAS 1225195-71-0)
- Bisoprolol Impurity 75 (CAS CATO-C4X-124775)
- Bisoprolol Impurity 65 (CAS CATO-C4X-124765)
Recommended Standards
- 69810-10-2 AC-24772 [1R-(1a,2b,3a,5a)]-5-Hydroxy-2-[(1-methoxy-1-methylethoxy)methyl]-3-[(tetrahydro-2H-pyran-2-yl)oxy]cyclopentaneheptanoic acid methyl ester (CAS 69810-10-2)
- Progesterone Impurity 90 (CAS CATO-C4X-150290)
- (2R)-3-(4-cyanophenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid (2R)-3-(4-cyanophenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propionic acid (2R)-3-(4-cyanophenyl)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]propanoic acid 205526-34-7 Fmoc-D-4-Cyanophe (CAS 205526-34-7)
- 9-Ketone Latanoprost (CAS 141074-06-8)
- Elagolix Impurity 11 (CAS 2248628-93-3)
- Maribavir Impurity 21 (CAS 217951-74-1)
- Atropine Impurity 51 (CAS CATO-C4X-148951)
- Methyl 4-bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylate (CAS 1159982-21-4)
- 5-(3-Fluorophenyl)-1h-pyrazole (CAS 149739-61-7)
- Methyl 2-(2,3-difluorophenyl)acetate (CAS 1036273-31-0)
- (4-Chloropicolinoyl)-l-leucine (CAS 956438-61-2)
- Thieno[2,3-b]thiophene-2-carboxylic acid (CAS 14756-75-3)
- 2-(O-tolyl)thiazole-5-carbaldehyde (CAS 915919-92-5)
- Neuropeptide FF (CAS 99566-27-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com