(E)-2-Cyano-3-(4-fluorophenyl)acrylic acid CAS 122520-74-5
| CAS No. | 122520-74-5 |
| Molecular Formula | C10H6FNO2 |
| Molecular Weight | 191.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C10H6FNO2, (E)-2-Cyano-3-(4-fluorophenyl)acrylic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 191.16 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
(E)-2-Cyano-3-(4-fluorophenyl)acrylic acid (CAS 122520-74-5) is a high-purity analytical reference standard with the molecular formula C10H6FNO2 and a molecular weight of 191.16 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H6FNO2 |
| Molecular Weight | 191.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related E Standards
- 2-Cyano-3-(4-fluorophenyl)prop-2-enoic acid (CAS 118409-66-8)
- (E)-3-(4-cyano-3-fluorophenyl)acrylic acid (CAS 1262013-21-7)
- (E)-3-(3-CYANO-2-FLUOROPHENYL)ACRYLIC ACID (CAS 1262014-59-4)
- (E)-3-(3-Cyano-4-fluorophenyl)acrylic acid (CAS 575469-19-1)
- (E)-3-(4-cyano-2-fluorophenyl)acrylic acid (CAS 669002-88-4)
- 4-Cyano-3-methoxy-5-methylbenzoic acid (CAS 116934-83-9)
- Methyl 2-(2-Cyano-4-hydroxyphenyl)acetate (CAS 1261559-90-3)
- methyl 2-(4-cyano-2-hydroxyphenyl)acetate (CAS 1261649-42-6)
Recommended Standards
- 5-Fluoroquinoline-4-carboxylic acid (CAS 1219834-23-7)
- 5-Fluoro-2-(pyridin-2-yl)pyrimidin-4(3H)-one (CAS 1240596-22-8)
- 2-Fluoro-4-(1H-1,2,4-triazol-1-yl)benzaldehyde (CAS 1216592-60-7)
- 6-Fluoro-2-(pyridin-2-yl)pyrimidin-4-ol (CAS 1240601-22-2)
- (E)-4-(3-(Hydroxy(phenyl)methylene)-2-(4-nitrophenyl)-4,5-dioxopyrrolidin-1-yl)butanoic acid (CAS 5961-32-0)
- 3,5-Difluoro-2,2-dimethylpropiophenone (CAS 898789-77-0)
- 3-Aminopyrazine-2-carbohydrazide (CAS 6761-52-0)
- 5-(3,5-Dichlorophenyl)-5-oxovaleric acid (CAS 172168-00-2)
- 2-Bromo-N-(4-butoxyphenyl)-2-methylpropanamide (CAS 23532-45-8)
- Montelukast Impurity 24 (CAS CATO-C4X-103124)
- (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(benzyloxy)butanoic acid (CAS 1313054-84-0)
- Betahistine Impurity 5 (CAS 6293-56-7)
- 2-(Aminomethyl)-4-(difluoromethyl)-6-hydroxypyridine-3-acetic acid (CAS 1805543-21-8)
- Fragment-[3-31]-Semaglutide (CAS CATO-C4X-2226113)
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