2-(2-(4-Fluorophenoxy)ethyl)-1,3-dioxolane CAS 1225504-15-3
| CAS No. | 1225504-15-3 |
| Molecular Formula | C11H13FO3 |
| Molecular Weight | 212.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2-(4-Fluorophenoxy)ethyl)-1,3-dioxolane.
2-(2-(4-Fluorophenoxy)ethyl)-1,3-dioxolane (CAS 1225504-15-3) is a high-purity analytical reference standard with the molecular formula C11H13FO3 and a molecular weight of 212.22 g/mol.
2-(2-(4-Fluorophenoxy)ethyl)-1,3-dioxolane (C11H13FO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(2-(4-Fluorophenoxy)ethyl)-1,3-dioxolane under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H13FO3 |
| Molecular Weight | 212.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Fluorophenoxy Standards
- Ethyl 3-(4-fluorophenoxy)propanoate (CAS 109174-29-0)
- Methyl 4-(2-fluorophenoxy)butanoate (CAS 1096828-31-7)
- Ethyl 3-(3-fluorophenoxy)propanoate (CAS 1099624-30-2)
- Ethyl 3-(2-fluorophenoxy)propanoate (CAS 1099670-07-1)
- 2-(2-(2-Fluorophenoxy)ethyl)-1,3-dioxolane (CAS 1225601-60-4)
- 2-(2-(3-Fluorophenoxy)ethyl)-1,3-dioxolane (CAS 1225601-99-9)
- 3-(3-Fluorophenoxy)-2,2-dimethylpropanoic acid (CAS 1267001-89-7)
- (5S)-5-((4-Fluorophenoxy)methyl)tetrahydrofuran-2-ol (CAS 220623-67-6)
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- Semaglutide impurity 196 (CAS CATO-C4X-2226196)
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