2-(3,4-Difluorophenyl)nicotinic acid CAS 1225511-07-8
| CAS No. | 1225511-07-8 |
| Molecular Formula | C12H7F2NO2 |
| Molecular Weight | 235.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 2-(3,4-Difluorophenyl)nicotinic acid (C12H7F2NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 235.19 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
2-(3,4-Difluorophenyl)nicotinic acid (CAS 1225511-07-8) is a high-purity analytical reference standard with the molecular formula C12H7F2NO2 and a molecular weight of 235.19 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(3,4-Difluorophenyl)nicotinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H7F2NO2 |
| Molecular Weight | 235.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluorophenyl Standards
- 6-(3,5-Difluorophenyl)-nicotinic acid (CAS 1033844-89-1)
- 5-(3,5-Difluorophenyl)nicotinic acid (CAS 1048267-36-2)
- 5-(3,4-Difluorophenyl)nicotinic acid (CAS 1048486-16-3)
- 5-(3,4-Difluorophenyl)-picolinic acid (CAS 1225477-53-1)
- 2-(3,5-Difluorophenyl)nicotinic acid (CAS 1225477-61-1)
- 2-(3,5-Difluorophenyl)isonicotinic acid (CAS 1225477-70-2)
- 2-(3,4-Difluorophenyl)isonicotinic acid (CAS 1225511-01-2)
- 6-(3,5-Difluorophenyl)picolinic acid (CAS 1226098-50-5)
Recommended Standards
- 4-(3,5-Difluorophenyl)picolinic acid (CAS 1255638-17-5)
- 4-(2,4-Difluorophenyl)picolinic acid (CAS 1258626-21-9)
- 2-(2,4-Difluorophenyl)isonicotinic acid (CAS 1258627-10-9)
- 2,6-Difluoro-4-(pyridin-3-yl)benzoic acid (CAS 1214372-01-6)
- 2-((6-Aminonaphthalen-2-yl)sulfonyl)ethan-1-ol (CAS 52218-35-6)
- 3,4-Dihydrobenzo[4,5]imidazo[1,2-a]pyridin-1(2H)-one (CAS 111211-54-2)
- 3-bromo-2-fluorofuran (CAS 163459-22-1)
- 4,6-Dihydroxynicotinamide (CAS 5466-41-1)
- 1-(2-Ethyl-hexyl)-4-methyl-piperidine (CAS 865074-78-8)
- (4-Cyano-3-methylphenyl)boronic acid (CAS 856255-58-8)
- Fedratinib D9 (CAS 936091-26-8 (Unlabeled))
- 4-Methoxy-1-phenyl-2-naphthamide (CAS 102028-28-4)
- Caspofungin Impurity 24 (CAS 1131958-73-0)
- Semaglutide Impurity 9 (CAS CATO-C4X-22269)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com