2-Chloro-4-(2-fluorophenyl)nicotinonitrile CAS 1225544-56-8

Description

Compared with other compounds in its class, the molecular weight of 232.64 g/mol gives 2-Chloro-4-(2-fluorophenyl)nicotinonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-Chloro-4-(2-fluorophenyl)nicotinonitrile (CAS 1225544-56-8) is a high-purity analytical reference standard with the molecular formula C12H6ClFN2 and a molecular weight of 232.64 g/mol.

2-Chloro-4-(2-fluorophenyl)nicotinonitrile (C12H6ClFN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Chloro-4-(2-fluorophenyl)nicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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