4-(2-fluorophenyl)-2-methylbutanoic acid CAS 1225852-32-3
| CAS No. | 1225852-32-3 |
| Molecular Formula | C11H13FO2 |
| Molecular Weight | 196.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(2-fluorophenyl)-2-methylbutanoic acid (CAS 1225852-32-3), molecular formula C11H13FO2 and molecular weight 196.22 g/mol, is a CATO reference standard with documented purity and traceability.
4-(2-fluorophenyl)-2-methylbutanoic acid (C11H13FO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H13FO2 |
| Molecular Weight | 196.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related fluorophenyl Standards
- (R)-2-(4-Fluorophenyl)-3-methylbutyric Acid (CAS 110311-45-0)
- 1-(3-Fluorophenyl)-4-methoxybutan-2-one (CAS 1179602-83-5)
- 2-(2-Fluorophenyl)-3-methylbutanoic acid (CAS 1181574-74-2)
- 3-(2-Fluorophenyl)-3-methylbutanoic acid (CAS 1226160-51-5)
- 4-(4-fluorophenyl)-2-methylbutanoic acid (CAS 1226160-80-0)
- 3-(2-Fluorophenyl)-2,2-dimethylpropanoic acid (CAS 1226161-12-1)
- 3-(3-Fluorophenyl)-2,2-dimethylpropanoic acid (CAS 1267669-89-5)
- 3-(4-Fluorophenyl)tetrahydro-2H-pyran-3-ol (CAS 1338990-25-2)
Recommended Standards
- 1-(5-Fluoro-2-hydroxyphenyl)-2,2-dimethylpropan-1-one (CAS 1225852-20-9)
- 1-(5-Fluoro-2-hydroxyphenyl)-3-methylbutan-1-one (CAS 1225523-32-9)
- 1-(2-Amino-4-fluorophenyl)-3-pyrrolidinol (CAS 1220037-41-1)
- (S)-2-Amino-N-(2-fluoro-4-methylphenyl)propanamide (CAS 1217825-52-9)
- Phosphoramidothioic Dichloride (CAS 14475-36-6)
- 6-((8-Methoxy-4,8-dimethylnonan-2-yl)oxy)-2,3-dihydrobenzofuran (CAS 51079-60-8)
- (R)-1-(6-Methoxypyridin-2-yl)ethan-1-amine hydrochloride (CAS 1391361-38-8)
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- 1-(5-(Methylsulfonyl)-6-oxo-1,6-dihydropyrimidin-2-yl)piperidine-3-carboxylic acid (CAS 1710844-94-2)
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- ((2S)-2-((2S,3S)-3-Amino-2-hydroxy-N-methyldecanamido)-4-(methylsulfinyl)butanoyl)-L-tyrosine (CAS 1135249-50-1)
- Crustacean Cardioactive Peptide (CCAP) (CAS 309247-84-5)
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