2-(4-(2-Chlorophenyl)-tetrahydro-2H-pyran-4-yl)acetic acid CAS 1226244-26-3
| CAS No. | 1226244-26-3 |
| Molecular Formula | C13H15ClO3 |
| Molecular Weight | 254.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(4-(2-Chlorophenyl)-tetrahydro-2H-pyran-4-yl)acetic acid (CAS 1226244-26-3), molecular formula C13H15ClO3 and molecular weight 254.71 g/mol, is a CATO reference standard with documented purity and traceability.
2-(4-(2-Chlorophenyl)-tetrahydro-2H-pyran-4-yl)acetic acid (C13H15ClO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-(2-Chlorophenyl)-tetrahydro-2H-pyran-4-yl)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H15ClO3 |
| Molecular Weight | 254.71 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
Related Chlorophenyl Standards
- N-(3-Chlorophenyl)-2-(morpholin-4-yl)acetamide (CAS 100388-40-7)
- 2-(4-Chlorophenyl)-4-phenyl-1H-imidazole (CAS 100558-20-1)
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)acetic acid (CAS 103182-06-5)
- (2E)-2-(4-Chlorophenyl)-3-(phenylamino)prop-2-enenitrile (CAS 1089302-54-4)
- 3-(2-Chlorophenyl)-1-cyclopropyl-1-(2-hydroxyethyl)urea (CAS 1155559-92-4)
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- 2-(3-Chlorophenyl)-2-(piperazin-1-yl)acetic acid (CAS 1218236-71-5)
- 2-(4-(3-Chlorophenyl)tetrahydro-2h-pyran-4-yl)acetic acid (CAS 1225768-54-6)
Recommended Standards
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- 5-Fluoro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole (CAS 1934467-26-1)
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- 2,5-Dichloro-3-fluorophenacyl chloride (CAS 1803819-30-8)
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- 1-(1-Pentyl-1H-indol-3-yl)-2-(m-tolyl)ethan-1-one (CAS 1427325-88-9)
- 4-(4-(4-Chlorobenzoyl)piperazin-1-yl)benzonitrile (CAS 478046-65-0)
- N-(5-Aminopentyl)-N-(4-methoxybenzyl)-N-methyl-N-2-pyridinyl-1,2-ethanediamine Dimaleate Salt (CAS 109912-42-7)
- Liraglutide Impurity 30 (CAS CATO-C4X-199230)
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