2-((2,6-Dichlorophenoxy)methyl)-1,3-dioxolane CAS 1226303-53-2
| CAS No. | 1226303-53-2 |
| Molecular Formula | C10H10Cl2O3 |
| Molecular Weight | 249.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-((2,6-Dichlorophenoxy)methyl)-1,3-dioxolane (CAS 1226303-53-2), a certified reference material (molecular formula C10H10Cl2O3, MW 249.09 g/mol) for analytical method development and quality control.
The molecular framework of 2-((2,6-Dichlorophenoxy)methyl)-1,3-dioxolane (C10H10Cl2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10Cl2O3 |
| Molecular Weight | 249.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
Related Dichlorophenoxy Standards
- 2-(2,5-Dichlorophenoxy)-2-methylpropanoic acid (CAS 103905-84-6)
- 2-(3,4-Dichlorophenoxy)-2-methylpropanoic acid (CAS 103905-85-7)
- methyl 3-(2,4-dichlorophenoxy)propanoate (CAS 1071715-08-6)
- Ethyl 2-(3,5-dichlorophenoxy)acetate (CAS 119024-29-2)
- 4-(2,6-Dichlorophenoxy)butanoic acid (CAS 119411-70-0)
- 2-((2,5-Dichlorophenoxy)methyl)-1,3-dioxolane (CAS 1226303-47-4)
- 2-((3,5-Dichlorophenoxy)methyl)-1,3-dioxolane (CAS 1226303-59-8)
- 2-(2,4-Dichlorophenoxy)propanehydrazide (CAS 15253-89-1)
Recommended Standards
- 4,5-Dichloro-2-(tetrahydro-2H-pyran-3-yl)pyridazin-3(2H)-one (CAS 1245649-65-3)
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- [2-(2,4-dichlorophenyl)-1,3-dioxolan-2-yl]methanol (CAS 112805-91-1)
- 2-Bromo-5,6-dihydro-4H-pyrrolo[3,2-d]thiazole-5-carboxylic acid (CAS 1263177-18-9)
- n-Methyltetrahydro-2h-thiopyran-3-amine (CAS 1409590-48-2)
- 2-Chloro-n-pentylpropanamide (CAS 87603-55-2)
- 3-Benzyloxy-6-bromo-2-fluorobenzaldehyde (CAS 1114809-05-0)
- 2-(4-(Difluoromethyl)-3-fluoro-5-iodopyridin-2-yl)acetonitrile (CAS 1806926-55-5)
- 2-[4-(5-Ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-(2-methoxyphenyl)acetamide (CAS 1775402-99-7)
- N-((2S,3S,E)-1,3-Dihydroxyoctadec-4-en-2-yl)acetamide (CAS 143615-69-4)
- 1-Methyl-1H-indole-2,3-dicarboxylic acid (CAS 121195-61-7)
- 2,4-Dimethylhexan-2-ol (CAS 42328-76-7)
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