2-Chloro-4-(4-chlorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile CAS 1226322-34-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1226322-34-4
Molecular FormulaC16H12Cl2N2
Molecular Weight303.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Chloro-4-(4-chlorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile CAS 1226322-34-4 chemical structure

Description

CATO supplies 2-Chloro-4-(4-chlorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 1226322-34-4), a certified reference material (molecular formula C16H12Cl2N2, MW 303.19 g/mol) for analytical method development and quality control.

The molecular framework of 2-Chloro-4-(4-chlorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile (C16H12Cl2N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Chloro-4-(4-chlorophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H12Cl2N2
Molecular Weight303.19 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentCl-containing
Nitrogen Atoms2

Related Chloro Standards

Recommended Standards

Why CATO?