2-(2-((4,6-Dimethylpyrimidin-2-yl)amino)thiazol-4-yl)-1-(4-(furan-2-carbonyl)piperazin-1-yl)ethan-1-one CAS 1226428-66-5
| CAS No. | 1226428-66-5 |
| Molecular Formula | C20H22N6O3S |
| Molecular Weight | 426.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(2-((4,6-Dimethylpyrimidin-2-yl)amino)thiazol-4-yl)-1-(4-(furan-2-carbonyl)piperazin-1-yl)ethan-1-one is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(2-((4,6-Dimethylpyrimidin-2-yl)amino)thiazol-4-yl)-1-(4-(furan-2-carbonyl)piperazin-1-yl)ethan-1-one (CAS 1226428-66-5), a certified reference material (molecular formula C20H22N6O3S, MW 426.49 g/mol) for analytical method development and quality control.
Based on its molecular formula C20H22N6O3S, 2-(2-((4,6-Dimethylpyrimidin-2-yl)amino)thiazol-4-yl)-1-(4-(furan-2-carbonyl)piperazin-1-yl)ethan-1-one contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 426.49 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(2-((4,6-Dimethylpyrimidin-2-yl)amino)thiazol-4-yl)-1-(4-(furan-2-carbonyl)piperazin-1-yl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H22N6O3S |
| Molecular Weight | 426.49 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Dimethylpyrimidin Standards
- 2-((4-(N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenyl)carbamoyl)benzoic acid (CAS 94134-30-2)
- 2-((4,6-Dimethylpyrimidin-2-yl)thio)-N-(5-(naphthalen-1-ylmethyl)thiazol-2-yl)acetamide (CAS 1848251-24-0)
- Ethyl 2-(2-(2-(2-((4,6-dimethylpyrimidin-2-yl)amino)thiazol-4-yl)acetamido)thiazol-4-yl)acetate (CAS 1226445-31-3)
- N-(2,6-dimethylpyrimidin-4-yl)-4-(((3-hydroxy-1-oxo-1H-inden-2-yl)methylene)amino)benzenesulfonamide (CAS 1024128-19-5)
- 6-(((4,6-Dimethylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 4-(trifluoromethyl)benzoate (CAS 877636-68-5)
- 6-(((4,6-Dimethylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 4-ethoxybenzoate (CAS 877635-57-9)
- 2-((4,6-Dimethylpyrimidin-2-yl)amino)-N-(4-morpholinophenyl)thiazole-4-carboxamide (CAS 1251563-89-9)
- 6-(((4,6-Dimethylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 2-chlorobenzoate (CAS 877635-63-7)
Recommended Standards
- N-(3-(6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-3-yl)phenyl)-5-(pyrrolidine-1-carbonyl)-1H-pyrrole-3-sulfonamide (CAS 1211237-89-6)
- 5-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1241950-72-0)
- Methyl 4-{[n-(pyridin-3-ylmethyl)4-methoxybenzenesulfonamido]methyl}benzoate (CAS 1000931-00-9)
- 4-(3-(4-(Methylthio)phenyl)-1,2,4-oxadiazol-5-yl)-2-(p-tolyl)phthalazin-1(2H)-one (CAS 1291832-21-7)
- 5-Isopropyldihydropyrimidine-2,4(1H,3H)-dione (CAS 650141-27-8)
- 1,1-Dimethylethyl (4S)-4-(4-hydroxyphenyl)-5-oxo-3-oxazolidinecarboxylate (CAS 1086703-01-6)
- 1-(2-Methyl-6-(phenylamino)pyridin-3-yl)propan-1-one (CAS 1355196-02-9)
- Dotriacontanoic acid (CAS 3625-52-3)
- N-(5-Isopropyl-1,3,4-thiadiazol-2-yl)-2,6-dimethoxybenzamide (CAS 82559-72-6)
- 4-Chloro-1-trityl-1H-pyrrolo[2,3-b]pyridine (CAS 2438941-56-9)
- 5-(3-Chloro-4-methoxyphenyl)furfural (CAS 124014-00-2)
- (2,5-Dimethylphenyl)(3-(morpholinomethyl)phenyl)methanone (CAS 898765-59-8)
- 4-Methoxy-3-methylbiphenyl (CAS 17171-17-4)
- Tirzepatide Impurity 34 (CAS CATO-C4X-324034)
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