4-(2-((2,4,6-Trifluorophenoxy)methyl)phenyl)piperidine hydrochloride CAS 1227056-87-2
| CAS No. | 1227056-87-2 |
| Molecular Formula | C18H18F3NO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(2-((2,4,6-Trifluorophenoxy)methyl)phenyl)piperidine hydrochloride (C18H18F3NOHCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4-(2-((2,4,6-Trifluorophenoxy)methyl)phenyl)piperidine hydrochloride (CAS 1227056-87-2) is a high-purity analytical reference standard with the molecular formula C18H18F3NOHCl and a molecular weight of 357.80 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(2-((2,4,6-Trifluorophenoxy)methyl)phenyl)piperidine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H18F3NO HCl |
| Molecular Weight | 357.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Trifluorophenoxy Standards
- 4-Methyl-2-(2,3,4-trifluorophenoxy)thiazole-5-carboxylic acid (CAS 1219562-35-2)
- 4-(2-((2,4,6-Trifluorophenoxy)methyl)phenyl)piperidine (CAS 1227056-84-9)
- 2-(2,3,4-Trifluorophenoxy)acetonitrile (CAS 1378309-94-4)
- 2-(3,4,5-Trifluorophenoxy)acetonitrile (CAS 1378379-03-3)
- 3-(3,4,5-Trifluorophenoxy)propanenitrile (CAS 1378674-13-5)
- 3-(2,3,4-Trifluorophenoxy)propanenitrile (CAS 1379223-03-6)
- 4-((3,4,5-Trifluorophenoxy)methyl)benzaldehyde (CAS 1443304-11-7)
- 5-(3,4,5-Trifluorophenoxy)pentanenitrile (CAS 1443304-16-2)
Recommended Standards
- 1-[(2-methylpropoxy)carbonyl]piperidine-4-carboxylic acid (CAS 1019363-04-2)
- (3S,4aS,8aS)-Decahydroisoquinolinecarboxylic Acid, Hydrochloride Salt (90%) (CAS 1221793-35-6)
- 3-(2-Fluorobenzoyl)-4-methylpyridin-2-amine (CAS 1485012-11-0)
- tert-Butyl 3-({[(benzyloxy)carbonyl]amino}methyl)azetidine-1-carboxylate (CAS 876149-42-7)
- Methyl 4-bromoisoquinoline-1-carboxylate (CAS 1512077-05-2)
- 1-Benzyl-4-bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 2377608-85-8)
- 2-((4-(Aminomethyl)benzyl)oxy)pyrimidin-4-amine (CAS 1004524-64-4)
- 1-(6-Methylpyridin-2-yloxy)propan-2-ol (CAS 1704065-86-0)
- 4,4-Difluoro-1-propylpiperidine (CAS 1159983-78-4)
- C-Peptide（dog） (CAS 39016-05-2)
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