6,6-difluoro-1-methyl-1,4-diazepane CAS 1227310-88-4
| CAS No. | 1227310-88-4 |
| Molecular Formula | C6H12F2N2 |
| Molecular Weight | 150.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6,6-difluoro-1-methyl-1,4-diazepane is closely related to fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 6,6-difluoro-1-methyl-1,4-diazepane (CAS 1227310-88-4), a certified reference material (molecular formula C6H12F2N2, MW 150.17 g/mol) for analytical method development and quality control.
The molecular framework of 6,6-difluoro-1-methyl-1,4-diazepane (C6H12F2N2) is characterized by fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6,6-difluoro-1-methyl-1,4-diazepane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H12F2N2 |
| Molecular Weight | 150.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related difluoro Standards
- [(2R)-4,4-Difluoro-1-methylpyrrolidin-2-yl]methanamine (CAS 1407997-79-8)
- (3,5-difluoro-4-pyridyl)methanamine (CAS 1416714-48-1)
- 3,3-Difluoro-1-methylpiperidin-4-amine (CAS 1439894-46-8)
- 4,4-Difluoro-1-methylcyclohexan-1-ol (CAS 1494596-57-4)
- 4,4-Difluoro-1-methylpiperidin-3-amine (CAS 1781798-41-1)
- (4,4-Difluoro-1-methylpyrrolidin-3-yl)methanamine (CAS 1784809-23-9)
- (2R)-6,6-Difluoro-2-methyl-1,4-diazepane (CAS 687634-54-4)
- 2-(3,3-Difluoro-pyrrolidin-1-yl)-ethylamine (CAS 867008-81-9)
Recommended Standards
- 3-Methylpentanedioic-2,2,4,4-d4 Acid (CAS 1219798-68-1)
- 4-Cyclopropoxyphenol (CAS 1243475-81-1)
- 2-Hydroxy-3’-methylacetophenone (CAS 121612-23-5)
- 1-(2,2-Difluoroethyl)pyrrolidin-3-amine (CAS 1247592-29-5)
- Methyl 3-(2-(2-morpholino-2-oxoacetyl)-1H-pyrrol-1-yl)thiophene-2-carboxylate (CAS 477857-72-0)
- 3-Bromo-1-naphthalenecarboxylic Acid (CAS 16726-66-2)
- 5-Chloro-3-iodo-1-(4-methylbenzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1241675-24-0)
- 11-Methylidene-4,10-dithia-1,8-diazatricyclo[7.3.0.0^{3,7}]dodeca-3(7),5,8-trien-2-one (CAS 126637-09-0)
- 2-(4-Isopropoxyphenyl)imidazole (CAS 1789876-14-7)
- 4,6-dichloro-1H-pyrazolo[3,4-d]pyrimidine-3-carbaldehyde (CAS 1378878-71-7)
- Ethyl 1-(4-aminophenyl)piperidine-3-carboxylate (CAS 889947-74-4)
- 1-Tosylpiperazine (CAS 27106-51-0)
- Mal(12.1) (CAS 1219008-68-0)
- MOTS-c Peptide (CAS 1627580-64-6)
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