1,3-Dioxa-8-azaspiro[4.5]Decan-2-one CAS 1227465-63-5
| CAS No. | 1227465-63-5 |
| Molecular Formula | C7H11NO3 |
| Molecular Weight | 157.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1,3-Dioxa-8-azaspiro[4.5]Decan-2-one.
CATO supplies 1,3-Dioxa-8-azaspiro[4.5]Decan-2-one (CAS 1227465-63-5), a certified reference material (molecular formula C7H11NO3, MW 157.17 g/mol) for analytical method development and quality control.
The molecular framework of 1,3-Dioxa-8-azaspiro[4.5]Decan-2-one (C7H11NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H11NO3 |
| Molecular Weight | 157.17 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 1 |
Related Dioxa Standards
- 1,4-Dioxa-9-azaspiro[4.5]decan-8-one (CAS 1312457-11-6)
- 1,8-Dioxa-3-azaspiro[4.5]decan-2-one (CAS 1486990-19-5)
- 3,8-dioxa-1-azaspiro[4.5]decan-2-one (CAS 1497905-45-9)
- 1,4-Dioxa-8-aza-spiro[4.5]decan-7-one (CAS 6813-54-3)
- 6,10-Dioxa-2-azaspiro[4.5]Decan-1-one (CAS 62987-17-1)
- 2-Methyl-1,3-dioxa-8-azaspiro[4.5]decane (CAS 112197-83-8)
- 1,8-Dioxa-4-azaspiro[5.5]undecane (CAS 1226975-76-3)
- 9-Ethyl-1,4-dioxa-7-azaspiro[4.4]nonane (CAS 1421603-46-4)
Recommended Standards
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- 2-(1-Methyl-2-oxo-1,2-dihydroquinolin-4-yl)acetic acid (CAS 4764-79-8)
- 2-Methoxy-6-nitrophenylacetic Acid (CAS 20876-28-2)
- N,N-DImethyl-6-pyrrolidin-2-ylpyridine-2-carboxamide dihydrochloride (CAS 1316219-08-5)
- 3H-Imidazo[4,5-b]pyridine-6-carbaldehyde (CAS 1022158-38-8)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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