6-Bromo-3-(bromomethyl)-2-chloropyridine CAS 1227509-75-2
| CAS No. | 1227509-75-2 |
| Molecular Formula | C6H4Br2ClN |
| Molecular Weight | 285.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Bromo-3-(bromomethyl)-2-chloropyridine (CAS 1227509-75-2) is a high-purity analytical reference standard with the molecular formula C6H4Br2ClN and a molecular weight of 285.36 g/mol.
The molecular framework of 6-Bromo-3-(bromomethyl)-2-chloropyridine (C6H4Br2ClN) is characterized by a nitrile group, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 6-Bromo-3-(bromomethyl)-2-chloropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4Br2ClN |
| Molecular Weight | 285.36 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 3-Bromo-5-(bromomethyl)-2-chloropyridine, 96% (CAS 1003859-11-7)
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