2,4-Difluoro-3-methylpyridine CAS 1227574-48-2
| CAS No. | 1227574-48-2 |
| Molecular Formula | C6H5F2N |
| Molecular Weight | 129.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,4-Difluoro-3-methylpyridine (CAS 1227574-48-2) is a high-purity analytical reference standard with the molecular formula C6H5F2N and a molecular weight of 129.11 g/mol.
The molecular framework of 2,4-Difluoro-3-methylpyridine (C6H5F2N) is characterized by a nitrile group, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,4-Difluoro-3-methylpyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H5F2N |
| Molecular Weight | 129.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 2,4-Difluoro-5-methylpyridine (CAS 1227502-70-6)
- 2,5-Difluoro-4-methylpyridine (CAS 1227508-13-5)
- 2,3-Difluoro-6-methylpyridine (CAS 1227579-04-5)
- 2,3-Difluoro-5-methylpyridine (CAS 1227597-78-5)
- 2,3-Difluoro-4-methylpyridine (CAS 1227597-92-3)
- 3,5-Difluoro-2-methylpyridine (CAS 1261799-90-9)
- 4,5-Difluoro-2-methylpyridine (CAS 1806304-13-1)
- 2,4-Difluoro-6-methylpyridine (CAS 83261-73-8)
Recommended Standards
- 2-Methyl-4,5-dihydrooxazole-4-carboxylic acid (CAS 114482-46-1)
- Methyl 4-oxoazetidine-2-carboxylate (CAS 111222-19-6)
- (E)-4-(methylamino)-4-oxobut-2-enoic acid (CAS 124378-37-6)
- (S)-Methyl 4-oxoazetidine-2-carboxylate (CAS 100188-44-1)
- 3-(4-Isopropoxyphenyl)-3-phenylpropanoic acid (CAS 672277-94-0)
- 1-Chloro-4-(1-chloropropan-2-yl)benzene (CAS 873379-28-3)
- 1-Methyl-3-(3-(triethoxysilyl)propyl)-1H-imidazol-3-ium chloride (CAS 338741-79-0)
- 3,7-Dibromo-6-hydroxy-4-methoxy-N-phenylbenzofuran-5-carboxamide (CAS 1373132-53-6)
- (1-Phenylethyl)(pyridin-4-ylmethyl)amine (CAS 289476-22-8)
- 1-Fluoro-4-nitro-2-(2,2,2-trifluoroethoxy)benzene (CAS 1881328-94-4)
- C-[2-(4-Fluoro-phenyl)-benzo[d]imidazo[2,1-b]-thiazol-3-yl]-methylamine (CAS 522651-98-5)
- 4-{1-[2-(dimethylamino)ethyl]-1H-indol-3-yl}butanoic acid (CAS 1094645-43-8)
- 1,3-Difluoro-2-(2-methoxyphenoxy)-5-(trifluoromethyl)benzene (CAS 2244088-69-3)
- Ac, Gastrin Releasing Peptide (20-27), porcine (CAS 77714-20-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com