4-(Chloromethyl)-6-fluoro-3,4'-bipyridine CAS 1227576-24-0
| CAS No. | 1227576-24-0 |
| Molecular Formula | C11H8ClFN2 |
| Molecular Weight | 222.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(Chloromethyl)-6-fluoro-3,4'-bipyridine (CAS 1227576-24-0) is a high-purity analytical reference standard with the molecular formula C11H8ClFN2 and a molecular weight of 222.65 g/mol.
4-(Chloromethyl)-6-fluoro-3,4'-bipyridine (C11H8ClFN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(Chloromethyl)-6-fluoro-3,4'-bipyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H8ClFN2 |
| Molecular Weight | 222.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloromethyl Standards
- 2-(4-(Chloromethyl)phenyl)-5-fluoropyrimidine (CAS 1139432-30-6)
- 4-(Chloromethyl)-3-fluoro-2,3'-bipyridine (CAS 1227511-72-9)
- 4-(Chloromethyl)-2-fluoro-3,4'-bipyridine (CAS 1227511-86-5)
- 4-(Chloromethyl)-3-fluoro-2,4'-bipyridine (CAS 1227588-73-9)
- 4-(Chloromethyl)-5-fluoro-2,3'-bipyridine (CAS 1227588-81-9)
- 4-(Chloromethyl)-6-fluoro-2,3'-bipyridine (CAS 1227605-48-2)
- 4-(Chloromethyl)-2-(4-fluorophenyl)pyrimidine (CAS 1339350-22-9)
- 5-(Chloromethyl)-3-(1-phenylethyl)-1,2,4-oxadiazole (CAS 1021436-49-6)
Recommended Standards
- 2-Chloro-6-methoxypyridine-3-sulfonamide (CAS 1208081-15-5)
- Methyl 3-(4-chlorophenyl)-2-isocyanopropanoate (CAS 120314-12-7)
- 4-chloro-6-(3-fluorophenyl)-2-methylpyrimidine (CAS 1256638-62-6)
- (2-Methoxypyrimidin-5-yl)methanesulfonyl chloride (CAS 1196155-67-5)
- Infigratinib Phosphate - API Standards (CAS 1310746-10-1)
- (3R,4R)-rel-1-(tert-Butoxycarbonyl)-4-(thiophen-2-yl)pyrrolidine-3-carboxylic acid (CAS 1330750-24-7)
- 1-(5-Hydroxy-4-methyltetrahydrofuran-3-yl)ethan-1-one (CAS 27098-03-9)
- Brexpiprazole Impurity 20 (CAS 616227-75-9)
- 1-Chloro-3-(2,4-dichlorophenyl)propan-2-one (CAS 90273-68-0)
- 2,2'-((3,5-Dimethoxyphenyl)azanediyl)diethanol (CAS 27076-89-7)
- 4-Chloro-N-ethyl-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide (CAS 2091679-00-2)
- 1-(3-Fluorophenyl)cyclohexane-1-carboxylic acid (CAS 214262-98-3)
- 2-Chloro-N-(4-chlorobenzyl)benzamide (CAS 367481-66-1)
- Semaglutide Impurity 161 (x TFA Salt) (CAS CATO-C4X-2226161)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com