3-(Bromomethyl)-2-methoxy-5-methylpyridine CAS 1227579-77-2
| CAS No. | 1227579-77-2 |
| Molecular Formula | C8H10BrNO |
| Molecular Weight | 216.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(Bromomethyl)-2-methoxy-5-methylpyridine (CAS 1227579-77-2) is a high-purity analytical reference standard with the molecular formula C8H10BrNO and a molecular weight of 216.08 g/mol.
The molecular framework of 3-(Bromomethyl)-2-methoxy-5-methylpyridine (C8H10BrNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(Bromomethyl)-2-methoxy-5-methylpyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10BrNO |
| Molecular Weight | 216.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromomethyl Standards
- 4-(Bromomethyl)-2-methoxy-3-methylpyridine (CAS 1227572-07-7)
- 3-(Bromomethyl)-6-methoxy-2-methylpyridine (CAS 1227575-85-0)
- 4-Bromomethyl-2-methoxy-6-methylpyridine (CAS 1227577-71-0)
- 3-(Bromomethyl)-2-methoxy-6-methylpyridine (CAS 1227594-67-3)
- 2-(Bromomethyl)-3-methoxyaniline (CAS 1261610-28-9)
- 5-(Bromomethyl)-2-methoxyaniline (CAS 1261861-37-3)
- 5-(Bromomethyl)-2-methoxy-3-methylpyridine (CAS 1379340-82-5)
- 2-(Bromomethyl)-5-ethoxypyridine (CAS 1517125-00-6)
Recommended Standards
- (r)-2-(1-Aminoethyl)-4-bromophenol (CAS 1228547-70-3)
- (S)-2-(1-aminoethyl)-4-bromophenol (CAS 1228571-89-8)
- 4-Bromo-3,5,6-trimethyl-1,2-dihydropyridin-2-one (CAS 121767-78-0)
- 2-Bromo-5-methoxy-N-methylaniline (CAS 1237027-05-2)
- 2-Bromo-5-(4,4-difluoropiperidin-1-yl)pyridine 1713163-41-7 (CAS 1713163-41-7)
- N-(6-((2-((4-Methylthiazol-2-yl)amino)-2-oxoethyl)thio)pyridazin-3-yl)isobutyramide (CAS 1021255-85-5)
- 1-Methoxynaphthalene-2-sulfonyl chloride (CAS 56875-52-6)
- 2-(Methylthio)-4-(trifluoromethyl)benzoic acid (CAS 142994-05-6)
- 2-(4,5-Dimethyl-1h-imidazol-1-yl)ethan-1-amine dihydrochloride (CAS 1390654-14-4)
- 6-bromo-3-ethyl-2-mercaptoquinazolin-4(3H)-one (CAS 18009-16-0)
- tert-Butyl 4-[(2-methoxy-2-oxoethyl)(methyl)-amino]piperidine-1-carboxylate (CAS 1306739-57-0)
- 2,4,7-Trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidine-6-carboxylic acid (CAS 918476-94-5)
- 5-Azaspiro[2.3]hexane-1-carboxylic acid (CAS 1534565-79-1)
- Semaglutide Impurity 151 xTFA (CAS CATO-C4X-2226151)
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