2-(2-Chloro-[3,4'-bipyridin]-4-yl)acetonitrile CAS 1227587-79-2
| CAS No. | 1227587-79-2 |
| Molecular Formula | C12H8ClN3 |
| Molecular Weight | 229.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(2-Chloro-[3,4'-bipyridin]-4-yl)acetonitrile (CAS 1227587-79-2), a certified reference material (molecular formula C12H8ClN3, MW 229.67 g/mol) for analytical method development and quality control.
The molecular framework of 2-(2-Chloro-[3,4'-bipyridin]-4-yl)acetonitrile (C12H8ClN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(2-Chloro-[3,4'-bipyridin]-4-yl)acetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8ClN3 |
| Molecular Weight | 229.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 4-Chloro-2-phenylpyrazolo[1,5-a]pyrazine (CAS 1019164-34-1)
- 5-Chloro-2-phenylpyrazolo[1,5-a]pyrimidine (CAS 1029720-21-5)
- 3-(4-Chloro-2-pyrimidinyl)-1H-Indole (CAS 1146080-35-4)
- 5-Chloro-2-phenyl-2H-benzo[d][1,2,3]triazole (CAS 118416-54-9)
- 2-(6-Chloro-[3,3'-bipyridin]-4-yl)acetonitrile (CAS 1227494-38-3)
- 2-(6-Chloro-[3,4'-bipyridin]-4-yl)acetonitrile (CAS 1227516-46-2)
- 2-(6-Chloro-[2,4'-bipyridin]-5-yl)acetonitrile (CAS 1227516-69-9)
- 2-(6-Chloro-[2,4'-bipyridin]-4-yl)acetonitrile (CAS 1227591-67-4)
Recommended Standards
- 2-(6-Chloro-[2,3'-bipyridin]-4-yl)acetonitrile (CAS 1227591-68-5)
- 2-(2-Chloro-[3,3'-bipyridin]-4-yl)acetonitrile (CAS 1227591-70-9)
- 1-(4-Amino-6-chloro-1,3,5-triazin-2-yl)piperidin-4-ol (CAS 1220016-80-7)
- 2-(6-Chloro-[3,4'-bipyridin]-5-yl)acetonitrile (CAS 1227591-72-1)
- 2-(Benzyl(methyl)amino)-2-phenylacetic acid hydrochloride (CAS 1956306-23-2)
- 4-(2,2-Difluoropropoxy)phenol (CAS 1783512-02-6)
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