2-(3-Chloro-5-fluoropyridin-2-yl)acetonitrile CAS 1227591-40-3
| CAS No. | 1227591-40-3 |
| Molecular Formula | C7H4ClFN2 |
| Molecular Weight | 170.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 2-(3-Chloro-5-fluoropyridin-2-yl)acetonitrile (CAS 1227591-40-3), a certified reference material (molecular formula C7H4ClFN2, MW 170.57 g/mol) for analytical method development and quality control.
2-(3-Chloro-5-fluoropyridin-2-yl)acetonitrile (C7H4ClFN2) contains a nitrile group, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H4ClFN2 |
| Molecular Weight | 170.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 3-Chloro-4-fluoro-1H-indazole (CAS 1000340-79-3)
- 7-Chloro-4-fluoro-1H-indazole (CAS 1000341-70-7)
- 4-Chloro-7-fluoro-1H-indazole (CAS 1000341-84-3)
- 2-(6-Chloro-5-fluoropyridin-3-yl)acetonitrile (CAS 1000557-28-7)
- 2-Chloro-6-fluoroimidazo[1,2-a]pyridine (CAS 1019020-11-1)
- 2-Chloro-8-fluoroimidazo[1,2-a]pyridine (CAS 1019021-98-7)
- 3-Chloro-6-fluoroimidazo[1,2-a]pyridine (CAS 1019026-23-3)
- 3-Chloro-8-fluoroimidazo[1,2-a]pyridine (CAS 1019028-15-9)
Recommended Standards
- 2-(5-Chloro-3-fluoropyridin-2-yl)acetonitrile (CAS 1227572-25-9)
- 2-(6-Chloro-2-fluoropyridin-3-yl)acetonitrile (CAS 1227598-89-1)
- 5-Chloro-6-fluoro pyridine-3-yl-acetonitrile (CAS 1227513-54-3)
- 2-(2-Chloro-5-fluoropyridin-3-yl)acetonitrile (CAS 1227606-64-5)
- 3-(tert-Butyl)-4-(2,6-diisopropoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole (CAS 2634687-76-4)
- 4-(9-Phenyl-9H-fluoren-9-yl)benzaldehyde (CAS 1186096-65-0)
- 2-(Benzyloxy)-4-methyl-5-nitropyridine (CAS 22754-93-4)
- (Tetrahydrofuran-2-yl)methyl 4-methylbenzenesulfonate (CAS 34583-63-6)
- 5-((3-Bromophenyl)amino)pyrimidine-4,6-diol (CAS 454685-37-1)
- 2-Allylphenol (CAS 1745-81-9)
- (1-Benzylpiperidin-4-yl)boronic acid (CAS 1251537-48-0)
- 5-Amino-1-(3-nitropyridin-2-yl)-1H-pyrazole-4-carbonitrile (CAS 956754-94-2)
- 3-Chloro-n-phenylbutanamide (CAS 90869-59-3)
- Semaglutide impurity 36 (CAS CATO-C4X-222636)
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