3-Chloro-2-methoxypyridin-4-ol CAS 1227600-52-3
| CAS No. | 1227600-52-3 |
| Molecular Formula | C6H6ClNO2 |
| Molecular Weight | 159.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C6H6ClNO2, 3-Chloro-2-methoxypyridin-4-ol contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 159.57 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
3-Chloro-2-methoxypyridin-4-ol (CAS 1227600-52-3), molecular formula C6H6ClNO2 and molecular weight 159.57 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H6ClNO2 |
| Molecular Weight | 159.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-(4-Chloro-1H-pyrazol-1-yl)acetamide (CAS 1006506-31-5)
- 6-Chloro-4-methoxypyridine-2(1H)-one (CAS 108279-65-8)
- 3-Chloro-5-methoxypyridine 1-oxide (CAS 110038-48-7)
- 5-Chloro-1-methyl-1H-pyrazole-4-carboxamide (CAS 110763-18-3)
- Methyl 4-chloro-1H-pyrrole-2-carboxylate (CAS 1194-96-3)
- 2-Chloro-6-methoxypyridin-3-ol (CAS 1196145-59-1)
- 6-Chloro-2-methoxypyridin-3-ol (CAS 1196146-98-1)
- 4-Chloro-6-methoxypyridin-3-ol (CAS 1196152-16-5)
Recommended Standards
- 3-Chloro-6-(hydroxymethyl)pyridin-2(1H)-one (CAS 1227600-29-4)
- 6-Chloro-5-(hydroxymethyl)pyridin-2-ol (CAS 1227602-36-9)
- Gimeracil Impurity N1 (CAS 1227600-22-7)
- 2-Chloro-6,7-dihydro-4H-pyrano[3,4-d]oxazole (CAS 1260671-76-8)
- 1-(2,4-Bis(benzyloxy)-3-iodophenyl)ethanone (CAS 936549-88-1)
- 2-(2-Chloroethyl)-5-phenyl-1,3-oxazole (CAS 70680-56-7)
- 3-(((3-Fluorobenzyl)oxy)methyl)-1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine (CAS 1306739-12-7)
- (1R,5S)-6-Azabicyclo[3.2.1]octan-7-one (CAS 6142-56-9)
- 2-Chloro-3-(difluoromethyl)-6-iodo-4-nitropyridine (CAS 1805270-36-3)
- 2-[N-(2-Methoxyethyl)methanesulfonamido]acetic acid (CAS 956019-97-9)
- 4-Chloro-1-butyne (CAS 51908-64-6)
- 2-Methyl-2-(5-methylfuran-2-yl)propan-1-amine (CAS 1248559-48-9)
- 2-Cyclopentylpropanoic acid (CAS 7028-22-0)
- Peptide Impurity 64 (CAS CATO-CPTD788964)
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