4-(bromomethyl)-3-fluoropyridine CAS 1227602-49-4
| CAS No. | 1227602-49-4 |
| Molecular Formula | C6H11BrFN |
| Molecular Weight | 196.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(bromomethyl)-3-fluoropyridine.
CATO supplies 4-(bromomethyl)-3-fluoropyridine (CAS 1227602-49-4), a certified reference material (molecular formula C6H11BrFN, MW 196.06 g/mol) for analytical method development and quality control.
The molecular framework of 4-(bromomethyl)-3-fluoropyridine (C6H11BrFN) is characterized by fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(bromomethyl)-3-fluoropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H11BrFN |
| Molecular Weight | 196.06 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related bromomethyl Standards
- 3-(bromomethyl)-5-fluoro-pyridine (CAS 120277-14-7)
- 2-(bromomethyl)-3-fluoro-pyridine (CAS 122307-44-2)
- 2-(bromomethyl)-3-fluoro-1-methyl-1H-pyrrole (CAS 2167791-25-3)
- 4-(Bromomethyl)-4-fluoropiperidine (CAS 2306276-64-0)
- 4-(Bromomethyl)-2-chlorooxazole (CAS 706789-08-4)
- 4-(Bromomethyl)tetrahydro-2H-thiopyran (CAS 1276056-87-1)
- 3-(Bromomethyl)-1-methoxypentane (CAS 1493588-60-5)
- 3-(Bromomethyl)-3-(difluoromethyl)cyclobut-1-ene (CAS 2452341-97-6)
Recommended Standards
- 4-bromo-2-fluoro-3-methylpyridine (CAS 128071-79-4)
- 4-bromo-5-fluoro-2-methyl-pyridine (CAS 1211590-24-7)
- 2,4-Dichloro-6-(methylthio)-1,3,5-triazine (CAS 13705-05-0)
- 3-bromo-5-fluoro-2-methylpyridine (CAS 1211542-29-8)
- 1-Cyclopentyl-4-iodo-3,5-dimethyl-1h-pyrazole (CAS 1521281-04-8)
- 3,6-Dimethyl-6,7-dihydroisoxazolo[5,4-b]pyridine (CAS 516500-11-1)
- Nitrocaramiphen hydrochloride (CAS 98636-73-8)
- 1-(Pyrrolidin-3-yl)-1h-indazole (CAS 1250918-60-5)
- Dimethyl (3-cyanobenzyl)phosphonate (CAS 287720-52-9)
- 2-((2-Chloropyrimidin-5-yl)oxy)acetonitrile (CAS 169677-65-0)
- N-(4-chloro-2-methylphenyl)-2-(N-(2,4-dichloro-5-methoxyphenyl)methylsulfonamido)acetamide (CAS 343374-20-9)
- 2-Methyl-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)-1H-indole-3-carbaldehyde (CAS 431910-43-9)
- 4-Methoxyquinazolin-7-amine (CAS 1556373-89-7)
- Ac-(5-31)Semaglutide (CAS CATO-C4X-2226279)
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