N-(5-Chloro-2-methoxyphenyl)-2-(10-(4-(2-hydroxyethyl)piperazine-1-carbonyl)-3,4-dihydrobenzo[b][1,6]naphthyridin-2(1H)-yl)acetamide CAS 1228168-54-4
| CAS No. | 1228168-54-4 |
| Molecular Formula | C28H32ClN5O4 |
| Molecular Weight | 538.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies N-(5-Chloro-2-methoxyphenyl)-2-(10-(4-(2-hydroxyethyl)piperazine-1-carbonyl)-3,4-dihydrobenzo[b][1,6]naphthyridin-2(1H)-yl)acetamide (CAS 1228168-54-4), a certified reference material (molecular formula C28H32ClN5O4, MW 538.04 g/mol) for analytical method development and quality control.
Based on its molecular formula C28H32ClN5O4, N-(5-Chloro-2-methoxyphenyl)-2-(10-(4-(2-hydroxyethyl)piperazine-1-carbonyl)-3,4-dihydrobenzo[b][1,6]naphthyridin-2(1H)-yl)acetamide contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 538.04 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(5-Chloro-2-methoxyphenyl)-2-(10-(4-(2-hydroxyethyl)piperazine-1-carbonyl)-3,4-dihydrobenzo[b][1,6]naphthyridin-2(1H)-yl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H32ClN5O4 |
| Molecular Weight | 538.04 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related N Standards
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- Methyl 2-[2-({4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}sulfonyl)-4,5-dimethoxyphenyl]acetate (CAS 1024415-60-8)
- 5-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-3-(3-methyl-5-oxo-1-phenyl-1,2,4-triazolidin-3-yl)-3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2]oxazole-4,6-dione (CAS 317822-46-1)
- (5E)-1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-5-({[4-(trifluoromethoxy)phenyl]amino}methylidene)-1,3-diazinane-2,4,6-trione (CAS 303144-34-5)
- 2-((4-Chloro-N-(3-(trifluoromethyl)phenyl)phenyl)sulfonamido)-N-(3,5-dichlorophenyl)acetamide (CAS 337922-29-9)
- 6-Chloro-2-iodo-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine (CAS 5987-76-8)
- 4-Chloro-N-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-N-(4-chlorobenzyl)benzenesulfonamide (CAS 338406-40-9)
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Recommended Standards
- N-(5-Acetamido-2-methoxyphenyl)-2-((4-(4-chlorophenyl)-5-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 476484-35-2)
- 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7-Pentadecafluoro-9-iododecane (CAS 25291-12-7)
- Tetrachlorantraniliprole (CAS 1104384-14-6)
- Niobium(V) oxalate (CAS 21348-59-4)
- 3-Ethyl-4-hydroxybenzamide (CAS 1243455-32-4)
- 4-Heptanol (CAS 589-55-9)
- 1-(2-Fluorophenyl)-4-[(5-phenyl-1,2-oxazol-3-yl)methyl]piperazine (CAS 339019-73-7)
- 2-(Methylthio)benzo[d]thiazole-6-carbonitrile (CAS 401567-19-9)
- CPI-1205 (CAS 1621862-70-1)
- 2-Methyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine (CAS 7546-38-5)
- Calcitriol Impurity 59 (CAS 934338-44-0)
- 4-(Difluoromethyl)pyridin-3-ol (CAS 1803997-29-6)
- Ethyl 2-((2-oxo-2h-chromen-7-yl)oxy)acetate (CAS 72000-18-1)
- Insulin Degludec Impurity 8 (CAS CATO-C4X-21578)
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