tert-Butyl (R)-3-(2,5-difluorophenyl)piperazine-1-carboxylate CAS 1228565-80-7
| CAS No. | 1228565-80-7 |
| Molecular Formula | C15H20F2N2O2 |
| Molecular Weight | 298.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), tert-Butyl (R)-3-(2,5-difluorophenyl)piperazine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
tert-Butyl (R)-3-(2,5-difluorophenyl)piperazine-1-carboxylate (CAS 1228565-80-7), molecular formula C15H20F2N2O2 and molecular weight 298.33 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, tert-Butyl (R)-3-(2,5-difluorophenyl)piperazine-1-carboxylate (C15H20F2N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 298.33 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C15H20F2N2O2 |
| Molecular Weight | 298.33 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- tert-Butyl (S)-3-(2,5-difluorophenyl)piperazine-1-carboxylate (CAS 1228559-49-6)
- tert-Butyl (S)-3-(2,3-difluorophenyl)piperazine-1-carboxylate (CAS 1228566-07-1)
- tert-Butyl (S)-3-(2,4-difluorophenyl)piperazine-1-carboxylate (CAS 1228558-90-4)
- 4-O-Benzyl Tyrosol α-Acetate 3-Aldehyde (CAS 1237517-66-6)
- (E)-4-(3-(3-Chlorophenyl)-3-oxoprop-1-en-1-yl)benzoic acid (CAS 2651958-61-9)
- tert-Butyl 4-(2-methylpyrimidin-5-yl)piperazine-1-carboxylate (CAS 1956380-47-4)
- 2-(4-sec-Butylphenyl)-8-chloroquinoline-4-carbonyl chloride (CAS 1160256-20-1)
- 2-Methoxy-3,6-dichlorobenzoic acid potassiumsalt (CAS 10007-85-9)
- 4-chloro-2-(2,2,2-trifluoroethyl)pyrazolo[3,4-d]pyrimidine (CAS 1450917-13-1)
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- Hex-4-yn-1-ylbenzene (CAS 34298-75-4)
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