(R)-1-(2-Fluoro-4-(trifluoromethyl)phenyl)propan-1-amine CAS 1228569-59-2
| CAS No. | 1228569-59-2 |
| Molecular Formula | C10H11F4N |
| Molecular Weight | 221.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(R)-1-(2-Fluoro-4-(trifluoromethyl)phenyl)propan-1-amine (CAS 1228569-59-2), molecular formula C10H11F4N and molecular weight 221.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (R)-1-(2-Fluoro-4-(trifluoromethyl)phenyl)propan-1-amine (C10H11F4N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (R)-1-(2-Fluoro-4-(trifluoromethyl)phenyl)propan-1-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H11F4N |
| Molecular Weight | 221.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related R Standards
- 8-Fluoro-4-hydroxyquinoline-3-carbohydrazide (CAS 1018127-67-7)
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- 1-(4-Fluoro-2-nitrophenyl)-2-methyl-1H-imidazole (CAS 1018150-88-3)
- 1-(2-Fluoro-4-methylphenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1040025-87-3)
- 1-(5-Fluoro-2-methylphenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1042534-83-7)
- 1-(3-Fluoro-4-methylphenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1042604-73-8)
- 1-(4-Fluoro-2-methylphenyl)-1h-1,2,3-triazole-4-carboxylic acid (CAS 1042604-81-8)
- 5-Fluoro-6-(phenylamino)pyrimidine-2,4(1H,3H)-dione (CAS 105950-49-0)
Recommended Standards
- (S)-1-(2-Fluoro-4-(trifluoromethyl)phenyl)propan-1-amine (CAS 1228554-01-5)
- (R)-1-(3-Fluoro-4-(trifluoromethyl)phenyl)propan-1-amine (CAS 1241677-13-3)
- 2-(4-Fluoro-3-(trifluoromethyl)phenyl)propan-2-amine (CAS 1226867-02-2)
- (S)-1-(3-fluoro-5-(trifluoromethyl)phenyl)propan-1-amine (CAS 1241678-11-4)
- 2-chlorothieno[3,2-d]pyrimidine-6-sulfonyl chloride (CAS 1955520-07-6)
- n-Ethyl-2-(2-(4-methoxyphenoxy)acetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide (CAS 503865-01-8)
- 1-(3-iodo-6-methyl-1h-indazol-1-yl)ethan-1-one (CAS 1788044-04-1)
- H-α-Me-DL-Trp-OMe (CAS 114524-80-0)
- Methyl 5-(5-methylfuran-2-yl)-1H-pyrazole-3-carboxylate (CAS 890591-48-7)
- Methyl (R)-3-(((benzyloxy)carbonyl)amino)-4-hydroxy-3-methylbutanoate (CAS 1802736-71-5)
- N-(2-(methylamino)ethyl)acetamide hydrochloride (CAS 1350720-14-7)
- 2-[(1-methyl-1H-1,3-benzodiazol-2-yl)sulfanyl]acetic acid (CAS 159222-24-9)
- Ethyl 2,2-difluoro-2-(phenylsulfonyl)acetate (CAS 130409-81-3)
- Peptide WE-14 (CAS 115136-18-0)
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