2-(3-(4-Chlorophenyl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)acetic acid CAS 1228650-22-3
| CAS No. | 1228650-22-3 |
| Molecular Formula | C10H8ClN3O3 |
| Molecular Weight | 253.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 253.64 g/mol gives 2-(3-(4-Chlorophenyl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)acetic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(3-(4-Chlorophenyl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)acetic acid (CAS 1228650-22-3), molecular formula C10H8ClN3O3 and molecular weight 253.64 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(3-(4-Chlorophenyl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)acetic acid (C10H8ClN3O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(3-(4-Chlorophenyl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8ClN3O3 |
| Molecular Weight | 253.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- Methyl 1-(2-chlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylate (CAS 1000576-85-1)
- 4-(3-Chlorophenyl)-1-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid (CAS 1355170-45-4)
- 1-{[(4-Chlorophenyl)carbonyl]oxy}pyrrolidine-2,5-dione (CAS 68388-09-0)
- 3-(4-Chlorophenyl)-6-methoxy-1,3,5-triazine-2,4(1H,3H)-dione (CAS 40943-38-2)
- 3-[(4-Chlorophenyl)(hydroxy)methyl]isoxazole-4-carboxylic Acid (CAS 2006277-75-2)
- (4-Chlorophenyl)(3,4-difluorophenyl)methanamine (CAS 1016697-79-2)
- Ethyl 3-(4-chlorophenyl)-4,5-dihydroisoxazole-5-carboxylate (CAS 109888-57-5)
- 1-[(4-Chlorophenyl)methyl]-5-oxopyrrolidine-2-carboxylic acid (CAS 116404-24-1)
Recommended Standards
- (3-Oxo-1,2,3,4-tetrahydroquinoxalin-2-ylidene)amino 2-chloroacetate (CAS 1221728-97-7)
- 3-(3-(2-Chloropyridin-4-yl)-1,2,4-oxadiazol-5-yl)propanoic acid (CAS 1255099-24-1)
- Ethyl 3-(2-chloropyridin-4-yl)-1,2,4-oxadiazole-5-carboxylate (CAS 1219571-90-0)
- Methyl (E)-2-(7-chloro-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-ylidene)acetate (CAS 1256633-11-0)
- 4-Amino-2,5-difluorophenol (CAS 120103-19-7)
- N-(2-chloro-5-(trifluoromethyl)phenyl)-2-(4-phenylpiperazin-1-yl)acetamide (CAS 297150-41-5)
- (S)-3-(2-bromophenoxy)butanoic acid (CAS 1416445-09-4)
- (E)-[(4-Fluorophenyl)methoxy][1-(5-methyl-1,2-oxazol-4-yl)ethylidene]amine (CAS 478049-28-4)
- (1,2-Dihydroacenaphthylen-5-yl)(phenyl)methanone (CAS 4657-89-0)
- 1-Oxaspiro[4.4]non-2-en-4-one (CAS 40990-01-0)
- 3-(6-(2-Fluorobenzoyl)-2-oxobenzo[d]oxazol-3(2H)-yl)propanoic acid (CAS 648410-54-2)
- 5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-N-{[(4-chlorophenyl)carbamothioyl]amino}-4,5-dihydro-1,2-oxazole-3-carboxamide (CAS 338399-35-2)
- (3,4-Dinitrophenyl)(morpholino)methanone (CAS 65003-28-3)
- (D-Ala1)-Peptide T amide (CAS 106362-34-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com