Tert-butyl (6-(3-(((tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-2-fluoropyridin-3-yl)carbamate CAS 1228665-49-3
| CAS No. | 1228665-49-3 |
| Molecular Formula | C21H36FN3O3Si |
| Molecular Weight | 425.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Tert-butyl (6-(3-(((tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-2-fluoropyridin-3-yl)carbamate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Tert-butyl (6-(3-(((tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-2-fluoropyridin-3-yl)carbamate (CAS 1228665-49-3), a certified reference material (molecular formula C21H36FN3O3Si, MW 425.61 g/mol) for analytical method development and quality control.
The molecular framework of Tert-butyl (6-(3-(((tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-2-fluoropyridin-3-yl)carbamate (C21H36FN3O3Si) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C21H36FN3O3Si |
| Molecular Weight | 425.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
- Jervine (CAS 469-59-0)
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- Orlistat Impurity 39 (CAS CATO-C4X-149939)
- N'-((2-Oxo-1,2-dihydroquinolin-3-yl)methylene)palmitohydrazide (CAS 881664-42-2)
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