2-Fluoro-6-(pyrrolidin-1-yl)nicotinonitrile CAS 1228665-87-9
| CAS No. | 1228665-87-9 |
| Molecular Formula | C10H10FN3 |
| Molecular Weight | 191.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C10H10FN3, 2-Fluoro-6-(pyrrolidin-1-yl)nicotinonitrile contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 191.20 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 2-Fluoro-6-(pyrrolidin-1-yl)nicotinonitrile (CAS 1228665-87-9), a certified reference material (molecular formula C10H10FN3, MW 191.20 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10FN3 |
| Molecular Weight | 191.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluoro Standards
- 5-Fluoro-2-(4-methyl-1h-pyrazol-1-yl)aniline (CAS 1006468-17-2)
- 3-Fluoro-4-(4-methyl-1h-pyrazol-1-yl)aniline (CAS 1006960-79-7)
- 1-(4-Fluoro-1h-indol-3-yl)propan-2-one (CAS 1018637-40-5)
- 3-Fluoro-N-(1h-imidazol-2-ylmethyl)aniline (CAS 1020670-43-2)
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Recommended Standards
- 4-(4-Fluorophenyl)-1-methyl-1h-imidazol-5-amine (CAS 1221725-63-8)
- 2-Fluoro-6-(pyrrolidin-1-yl)isonicotinonitrile (CAS 1228666-18-9)
- 1-(2-Fluorobenzyl)-1H-imidazol-2-amine (CAS 1216191-87-5)
- 4-(3-fluorophenyl)-3-methyl-1H-pyrazol-5-amine (CAS 1229025-29-9)
- 6-((3,5-Bis(trifluoromethyl)benzyl)thio)imidazo[2,1-b]thiazole-5-carbonitrile (CAS 400080-16-2)
- 5-Amino-2-chlorobenzenethiol (CAS 97094-83-2)
- 3-Cyclopropoxy-5-methylbenzaldehyde (CAS 1243358-25-9)
- Cyclohexyl 4-amino-4-methylpentanoate (CAS 1250230-31-9)
- 2-((1-(Pyridin-3-yl)ethyl)amino)propan-1-ol (CAS 1154987-59-3)
- Milnacipran Impurity N13 (CAS 105310-75-6)
- 1-(3,3,3-Trifluoropropyl)piperidin-3-one (CAS 1519490-46-0)
- 4,6-Difluoropyridine-2-carboxylic acid sodium salt (CAS 2173991-61-0)
- 3-Ethyl-1-vinylimidazolium Bis(trifluoromethanesulfonyl)imide (CAS 319476-28-3)
- D-Ala18-Tirzepatide (CAS CATO-CPTD788916)
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