6-Iodo-7-methyl-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one CAS 1228666-16-7
| CAS No. | 1228666-16-7 |
| Molecular Formula | C8H13IN2O2 |
| Molecular Weight | 296.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
6-Iodo-7-methyl-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one (CAS 1228666-16-7) is a high-purity analytical reference standard with the molecular formula C8H13IN2O2 and a molecular weight of 296.11 g/mol.
The molecular framework of 6-Iodo-7-methyl-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one (C8H13IN2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H13IN2O2 |
| Molecular Weight | 296.11 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
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